75180-50-6

Basic information

• Product Name: C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE
• Synonyms: RARECHEM AL BW 1266;C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE;[1-(4-FLUOROPHENYL)CYCLOPENTYL]METHANAMINE;OTAVA-BB 1059579;1-[1-(4-fluorophenyl)cyclopentyl]methanamine(SALTDATA: FREE);1-(4-Fluorophenyl)-cyclopentaneMethanaMine
• CAS NO: 75180-50-6
• Molecular Formula: C₁₂H₁₆FN
• Molecular Weight: 193.26
• Mol File: 75180-50-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE(75180-50-6)
• EPA Substance Registry System: C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE(75180-50-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 75180-50-6(Hazardous Substances Data)

Usage

General Description

C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE is a chemical compound with the molecular formula C13H18FN. It is an amine derivative, with a cyclopentyl ring substituted with a 4-fluoro-phenyl group and a methylamine group. C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE may have applications in medicinal chemistry, particularly in the development of new drugs and pharmaceuticals. Its unique structure and functional groups could potentially make it useful for targeting specific biological pathways or receptors in the human body. Further research and testing will be necessary to determine its potential uses and properties.

Upstream product

• 83706-50-7 1-(4-fluorophenyl)cyclopentane-1-carbonitrile 
• 459-22-3 4-fluorophenylacetonitrile 

Downstream Products

• 1338349-08-8 1-benzyl-N-{[1-(4-fluorophenyl)cyclopentyl]methyl}piperidine-4-carboxamide hydrochloride 

Relevant articles and documents

Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4- fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents

We synthesized and evaluated inhibitory activity against T-type Ca 2+ channels for a series of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl) butyl]piperidine-4-carboxamide derivatives. Structure-activity relationship studies have revealed that dialkyl substituents at the benzylic position play an important role in increasing inhibitory activity. Oral administration of N-[2-ethyl-2-(4-fluorophenyl)butyl]-1-(2-phenylethyl)piperidine-4-carboxamide (20d) lowered blood pressure in spontaneously hypertensive rats without inducing reflex tachycardia, which is often caused by traditional L-type Ca2+ channel blockers.