75180-50-6 Usage
Uses
Used in Pharmaceutical Development:
C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE is used as a chemical intermediate in the development of new pharmaceuticals for various therapeutic applications. Its unique structure allows it to potentially interact with specific biological targets, making it a valuable component in the creation of innovative drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE serves as a key compound for research purposes. Scientists and researchers utilize its distinctive properties to explore new avenues in drug discovery and to understand the mechanisms of action for potential therapeutic agents.
Used in Drug Design and Synthesis:
C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE is used as a building block in the design and synthesis of novel drug molecules. Its cyclopentyl and 4-fluoro-phenyl moieties, along with the methylamine group, provide a versatile template for the creation of compounds with specific pharmacological properties.
Used in Targeted Drug Delivery Systems:
C-[1-(4-FLUORO-PHENYL)-CYCLOPENTYL]-METHYLAMINE may also be employed in the development of targeted drug delivery systems. Its ability to bind to particular biological receptors could be leveraged to enhance the selectivity and efficacy of drug delivery, thereby improving treatment outcomes for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 75180-50-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,1,8 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75180-50:
(7*7)+(6*5)+(5*1)+(4*8)+(3*0)+(2*5)+(1*0)=126
126 % 10 = 6
So 75180-50-6 is a valid CAS Registry Number.
75180-50-6Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4- fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents
Watanuki, Susumu,Matsuura, Keisuke,Tomura, Yuichi,Okada, Minoru,Okazaki, Toshio,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi
, p. 5628 - 5638 (2011/10/12)
We synthesized and evaluated inhibitory activity against T-type Ca 2+ channels for a series of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl) butyl]piperidine-4-carboxamide derivatives. Structure-activity relationship studies have revealed that dialkyl substituents at the benzylic position play an important role in increasing inhibitory activity. Oral administration of N-[2-ethyl-2-(4-fluorophenyl)butyl]-1-(2-phenylethyl)piperidine-4-carboxamide (20d) lowered blood pressure in spontaneously hypertensive rats without inducing reflex tachycardia, which is often caused by traditional L-type Ca2+ channel blockers.
