75190-88-4Relevant academic research and scientific papers
A new strategy for the synthesis of 4,6-di-tert-butyl-2,2-dipentyl-2,3- dihydro-5-benzofuranol (BO-653), a potent antiatherogenic antioxidant
Murakata, Masatoshi,Kimura, Masahiro
scheme or table, p. 4950 - 4952 (2011/01/04)
An efficient alternative route to 4,6-di-tert-butyl-2,2-dipentyl-2,3- dihydro-5-benzofuranol (BO-653), a potent antiatherogenic antioxidant, has been developed by the application of the base-promoted dienone- phenol rearrangement reaction. A decisive effect of MgBr2 in the reaction of Grignard reagents is also described.
