75201-62-6Relevant academic research and scientific papers
Synthesis and QSAR modeling 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl] ethanones as potential antibacterial agents
Sahu, Vinita,Sharma, Pratibha,Kumar, Ashok
, p. 2476 - 2485 (2013/07/26)
The present communication deals with the synthesis of a series of 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl]ethanones. The compounds were synthesized in excellent yields (70-80 %), and the structures were established on the basis of consistent IR, 1H NMR, and elemental analysis data. The purity has been ascertained by chromatographic resolution using hexane-ethyl acetate (6:4 v/v) as binary eluent. All the compounds have been tested for their antimicrobial activity against a representative panel of bacteria i.e., Bacillus subtilis, Escherichia coli, Pseudomonas diminuta, and Staphylococcus aureus using Chloramphenicol as reference drug. All the synthesized compounds were found to exhibit profound antimicrobial activity.
Pyridazine derivatives and related compounds. 23*. synthesis of 3-substituted pyrazolo[3,4-c] pyridazines and their application as disperse dyes
Deeb,Yassin,Ouf,Shehta
experimental part, p. 212 - 222 (2011/08/21)
Acetylacetone and malononitrile were coupled with diazotized arylamines to give arylazoacetylacetones and arylazomalononitriles. When refluxed with 3-hydrazino-4,5-diphenyl-1H-pyrazolo-[3,4-c]pyridazine in the presence of ethanol/HCl, they yielded the corresponding 3-[4-(arylazo)-3,5-dimethylpyrazol- 1-yl]- and 3-[3,5-diamino-4-(arylazo)pyrazol-1-yl]-4,5-diphenyl-1H-pyrazolo[3,4- c]pyridazine dyes. The dyes were applied to polyester and polyamide fabrics, and their spectral and fastness properties were measured.
