75220-80-3

Basic information

• Product Name: 1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenyl-
• CAS NO: 75220-80-3
• Molecular Formula: C22H20N2
• Molecular Weight: 312.414
• Mol File: 75220-80-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenyl-(75220-80-3)
• EPA Substance Registry System: 1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenyl-(75220-80-3)

Safety Data

• Hazardous Substances Data: 75220-80-3(Hazardous Substances Data)

Usage

Molecular structure

1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenylis a chemical compound with a complex molecular structure.

Class of compounds

It belongs to the class of benzodiazepines.

Properties

Benzodiazepines are widely used as central nervous system depressants and have sedative, hypnotic, and anxiolytic properties.

Derivative

This particular compound is a derivative of 1,5-benzodiazepine.

Characteristic moiety

It is characterized by the presence of a 2,3-dihydro-4-(4-methylphenyl)-2-phenylmoiety.

Pharmaceutical research and drug development

It is used in pharmaceutical research and drug development for potential therapeutic applications.

Biological activities and mechanisms of action

Its specific biological activities and mechanisms of action are not fully understood.

Complex chemical compound

1H-1,5-Benzodiazepine, 2,3-dihydro-4-(4-methylphenyl)-2-phenylis a complex chemical compound with potential pharmacological significance.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 
• 93021-70-6 1-phenyl-3-(p-tolyl)prop-2-yn-1-ol 

Relevant articles and documents

Construction of the 1,5-Benzodiazepine Skeleton from o-Phenylendiamine and Propargylic Alcohols via a Domino Gold-Catalyzed Hydroamination/Cyclization Process

The gold-catalyzed reaction of o-phenylendiamine with propargylic alcohols affords 1,5-benzodiazepines bearing different substituents on the 2 and 4 positions. The method allows even for the selective preparation of 4-substituted 1,5-benzodiazepine derivatives.

Protic acidic ionic liquids promoted formation of 1,5-benzodiazepines: Remarkable effects of cations and anions on their performances

A series of protic acidic ionic liquids have been used as solvents and catalysts for the synthesis of 1,5-benzodiazepines. Success of the condensation appears to lie in the choice of cation-anion combinations and the ionic liquid [HBIm]CF3SOsu

NEW ASPECTS OF THE CHEMISTRY OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE

Under basic catalysis conditions the reaction of 4- and 4'-substituted chalcones with o-phenylenediamine leads to 2,3-dihydro-2,4-diaryl-1H-1,5-benzodiazepines; β-amino adducts, the ability of which to undergo intramolecular condensation increases as the