752201-70-0

Basic information

• Product Name: [2-(6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-ethyl]-phenyl-carbamic acid benzyl ester
• Synonyms: [2-(6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-ethyl]-phenyl-carbamic acid benzyl ester
• CAS NO: 752201-70-0
• Molecular Weight: 446.546
• Mol File: 752201-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-ethyl]-phenyl-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-ethyl]-phenyl-carbamic acid benzyl ester(752201-70-0)
• EPA Substance Registry System: [2-(6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-ethyl]-phenyl-carbamic acid benzyl ester(752201-70-0)

Safety Data

• Hazardous Substances Data: 752201-70-0(Hazardous Substances Data)

Relevant articles and documents

Synthesis and conformational analysis of 1,3,2-diazaphosphorino[6,1-a] isoquinolines, a new ring system

Through ring-closure reactions of N- or 1′-substituted 1-(2′-aminoethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines (5a-e) with phenylphosphonyl dichloride, 1- or 3-substituted 4-phenyl-1,3,4,6,7,11b- tetrahydro-2H-1,3,2-diazaphosphorino[6,1-a]isoquinolin-4-one diastereomers (7a-e and 8a-c,e), the first representatives of a new ring system, were prepared. The diastereomeric ratios in the cyclizations and the conformer (A-E) populations of the nitrogen-bridged tricyclic systems (7 and 8) were strongly influenced by the N- and 1′-substituents of the starting diamines. The conformational analysis of compounds 7 and 8 was performed by 1H, 13C and 31P NMR methods.