752234-64-3

Usage

Uses

Used in Pharmaceutical Industry:
1,2-DIHYDRO-5-METHOXY-2-OXO-SPIRO[3H-INDOLE-3,4'-PIPERIDINE]-1'-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER is used as a potential candidate for drug development for neurological and psychiatric disorders due to its unique structure and functional groups that may interact with specific biological targets.
However, it is important to note that the provided materials do not specify any particular applications or industries for 1,2-DIHYDRO-5-METHOXY-2-OXO-SPIRO[3H-INDOLE-3,4'-PIPERIDINE]-1'-CARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER beyond the general mention of its potential use in the pharmaceutical industry. Further research and testing are required to fully understand its properties, efficacy, and safety profile before it can be applied in any specific therapeutic area or industry.

Upstream product

• 1258637-92-1 5-methoxyspiro[indole-3,4'-piperidin]-2(1H)-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 752234-63-2 1'-benzyl-5-methoxyspiro[indole-3,4'-piperidin]-2(1H)-one 
• 59-48-3 2-oxoindole 
• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 

Relevant academic research and scientific papers

SPIRO-SUBSTITUTED PYRROLOPYRIMIDINES

The invention provides compounds of formula (I) or a pharmaceutically acceptable salt or ester thereof formula (I) wherein the symbols have the meaning as defined in the description. Said compounds are inhibitors of cathepsin K and/or cathepsin S and are useful for the treatment of diseases and medical conditions in which cathepsin K and/or cathepsin S is implicated, e.g. various disorders including neuropathic pain, inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis, multiple sclerosis and tumours.

2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF

The invention relates to pyrrolo pyrimidines of formula (I), wherein Y represents -(CH2)t-O- or -(CH2)r-S-, p is 1 or 2, r is 1, 2 or 3, t is 1, 2 or 3, or Y is -(CH2)j- or -CH=CH-, j is 1 or 2; p is 1 or 2, or Y is -(CH2)f-, f is 1 or 2, p is 1, and the further radicals and symbols have the meaning as defined herein; their preparation, their use as pharmaceuticals, pharmaceutical compositions containing them, the use of such a compound for the manufacture of a pharmaceutical preparation for the treatment of neuropathic pain and to a method for the treatment of such a disease in animals, especially in humans.