752243-43-9

Basic information

• Product Name: 1-[4-fluoro-3-(morpholine-4-carbonyl)-benzenesulfonyl]-piperidine-4-carboxylic acid
• CAS NO: 752243-43-9
• Molecular Weight: 400.428
• Mol File: 752243-43-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-fluoro-3-(morpholine-4-carbonyl)-benzenesulfonyl]-piperidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-fluoro-3-(morpholine-4-carbonyl)-benzenesulfonyl]-piperidine-4-carboxylic acid(752243-43-9)
• EPA Substance Registry System: 1-[4-fluoro-3-(morpholine-4-carbonyl)-benzenesulfonyl]-piperidine-4-carboxylic acid(752243-43-9)

Safety Data

• Hazardous Substances Data: 752243-43-9(Hazardous Substances Data)

Upstream product

• 7304-32-7 2-fluoro-5-nitrobenzoic acid 
• 498-94-2 isonipecotic acid 
• 752243-42-8 (5-amino-2-fluoro-phenyl)-morpholin-4-yl-methanone 
• 709-46-6 2-fluoro-5-nitrobenzoyl chloride 

Downstream Products

• 312722-59-1 4-{2-[(2,2-diphenyl-ethyl)-amino]-5-{[4-[4-(1-methyl-ethyl)-piperazin-1-yl-carbonyl]-piperidin-1-yl]-sulfonyl}-benzoyl}-morpholine 
• 752243-41-7 {2-(2,2-diphenyl-ethylamino)-5-[4-(4-carboxy)-piperidine-1-sulfonyl]-phenyl}-morpholin-4-yl-methanone 

Relevant articles and documents

Potent and orally bioavailable non-peptide antagonists at the human bradykinin B1 receptor based on a 2-alkylamino-5-sulfamoylbenzamide core

The bradykinin B1 receptor is rapidly induced after inflammation or tissue trauma and appears to play an important role in the maintenance of hyperalgesia in inflammatory conditions. Here, we describe the optimization process to identify novel,