752257-66-2

Basic information

• Product Name: 5-benzoylamino-1,3,4-triphenyl-2-pyrazoline-5-carbohydrazide
• Synonyms: 5-benzoylamino-1,3,4-triphenyl-2-pyrazoline-5-carbohydrazide
• CAS NO: 752257-66-2
• Molecular Weight: 475.55
• Mol File: 752257-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-benzoylamino-1,3,4-triphenyl-2-pyrazoline-5-carbohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzoylamino-1,3,4-triphenyl-2-pyrazoline-5-carbohydrazide(752257-66-2)
• EPA Substance Registry System: 5-benzoylamino-1,3,4-triphenyl-2-pyrazoline-5-carbohydrazide(752257-66-2)

Safety Data

• Hazardous Substances Data: 752257-66-2(Hazardous Substances Data)

Upstream product

• 145383-25-1 1,3,4,7-Tetraphenyl-8-oxa-1,2,6-triaza-spiro[4.4]nona-2,6-dien-9-one 

Relevant articles and documents

Synthesis and reactions of some new heterocyclic carbohydrazides and related compounds as potential anticancer agents

Acylation of 3-hydrazino-5,6-diphenyl-1,2,4-triazine (2) and hydrazine hydrate (7) with 4-aryl-1,3,7-triphenyl-8-oxa-1,2,6-triazaspiro[4.4]nona-2,6- dien-9-ones 5a,b gave the corresponding heterocyclic carbohydrazides 6a,b and 8a,b respectively. Conversion of compounds 8a,b into the versatile carbohydrazide derivatives 9a-g, 10, 13 and the related oxadiazoles 11, 12a,b was undertaken. A primary in vitro test of compound 8a (concentration 10 -4M) showed activity against leukemia cell lines (CCRF-CEM, K-256, MOLT-4, PRMI-8226, SR).