75228-33-0Relevant academic research and scientific papers
Diamine derivatives
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, (2008/06/13)
A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.
ETHYLENEDIAMINE DERIVATIVES
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, (2008/06/13)
The invention relates a compound represented by the formula (1):Q1-Q2-C(=O)-N(R1)-Q3-N(R2)-T1-Q4 wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents -CO- or -SO2-, and a medicine which comprises the compound and is useful for thrombosis and embolism.
KINETICS OF THE REACTION OF ALICYCLIC MONOEPOXIDES WITH CARBOXYLIC ACIDS
Batog, A. E.,Stepko, O. P.,Nikonova, L. P.
, p. 971 - 975 (2007/10/02)
Alicyclic monoepoxides and monocyclohexyl esters of 4-cyclohexene-1,2-dicarboxylic and 5-norbornene-2,3-dicarboxylic acids were synthesized.The kinetics of the nonkatalytic reaction of the monoepoxides with carboxylic acids in the mass at 100-160 deg C we
