75247-99-3

Upstream product

• 74360-64-8 1-<(ethoxycarbonyl)methyl>-2-benzylpyridinium bromide 

Downstream Products

• 118860-89-2 3-(2-oxo-3-indolylidene)-1-phenylindolizin-2-one 
• 107933-95-9 (2,3-dihydro-2-oxo-1-phenylindolizin-3-yl)-(2-hydroxy-1-phenylindolizin-3-yl)-(piperonyl)methane 
• 107934-05-4 2,3-dihydro-3-<4-(nitrophenyl)hydrazono>-1-phenylindolizin-2-one 
• 107934-04-3 2,3-dihydro-3-(phenylhydrazono)-1-phenylindolizin-2-one 
• 107933-97-1 2,3-dihydro-3-(3-hydroxy-2-oxo-3-indolyl)-1-phenyl-indolizin-2-one 
• 75248-32-7 2-acetyl-1-phenylindolizine 
• 84935-39-7 (Z)-2-(2-Acetoxy-1-phenyl-indolizin-3-yl)-but-2-enedioic acid dimethyl ester 
• 84920-13-8 2-(2-Acetoxy-1-phenyl-indolizin-3-ylmethylene)-malonic acid diethyl ester 
• 75248-05-4 3,3-Dibenzyl-1-phenyl-indolizin-2-one 
• 75248-06-5 3,3-Diallyl-1-phenyl-indolizin-2-one 
• 107933-94-8 (2,3-dihydro-2-oxo-1-phenylindolizin-3-yl)-(2-hydroxy-1-phenylindolizin-3-yl)-<4-(dimethylamino)phenyl>methane 
• 107934-02-1 2,3-dihydro-3-<4-(dimethylamino)phenylimino>-1-phenylindolizin-2-one 
• 107933-96-0 (2,3-dihydro-2-oxo-1-phenylindolizin-3-yl)-<(2-hydroxy-1-phenylindolizin-3-yl)-dimethyl>methane 
• 75248-35-0 ethyl 2-oxo-10-phenyl-2H-pyrano<2,3-b>indolizine-3-carboxylate 

Relevant academic research and scientific papers

Isomers and Aza-analogues of Indoxyl Containing Nitrogen at a Ring-fusion Position: Coupling Reactions with Electrophiles and Attempted Oxidations

Derivatives of four series of compounds derived from isomers of indoxyl with the nitrogen at the bridgehead and two further series of aza-analogues are prepared and their absorption properties studied.

Preparation of New Nitrogen-Bridged Heterocycles. 5. Smooth Michael Additions of 2(3H)-Indolizinone Derivatives

Michael additions of some 2(3H)-indolizinone derivatives to α,β-unsaturated nitriles, esters, and an amide gave the corresponding double Michael adducts, 3,3-disubstituted 2(3H)-indolizinones, in moderate to high yields, and those to methyl vinyl ketone a

Preparation of New Nitrogen-Bridged Heterocycles. Synthesis and Some Reactions of 2,3-Dihydroindolizin-2-one Derivatives

Alkaline treatment of 1--2-picolinium halides 1-5 in ethanol afforded the intramolecular condensation products, 2,3-dihydroindolizin-2-one derivatives 6-10, with the formation of the pyridine base.The possibility of the aromatic enol tautomer for the structures of 6-10 was excluded completely by the inspection of their IR and NMR spectra.The reactions of dihydroindolizinones 9 and 10 and pyridinium salts 1-5 with some alkylating and acylating agents in the presence of alkali gave 3,3-dialkyl- (19-40) and 3-spiro-2,3-dihydroindolizin-2-ones (45-50) and 2-alkoxy- (52, 53, and 57-63) and 2-(acyloxy)indolizines (64 and 65), while those with a bifunctional reagent such as diethyl (ethoxymethylene)malonate afforded tricyclic 2H-pyrano-indolizin-2-one derivatives 67-69.The mechanisms of the alkylation and the acylation could be well explained by the application of the HSAB principle to the ambident anion generated by the alkaline treatment of 2,3-dihydroindolizin-2-ones 6-10.