75288-21-0

Upstream product

• 50434-36-1 4-nitrophenylacetyl chloride 
• 104-03-0 4-nitrobenzeneacetic acid 

Downstream Products

• 85259-33-2 bromo-(4-nitrophenyl)acetic acid methyl ester 
• 4578-72-7 2-bromo-2-(4-nitrophenyl)acetic acid 
• 54342-51-7 3-hydroxy-2-(4-nitrobenzyl)pyridine 
• 82124-30-9 5-(4-acetamidophenyl)thiazolidine-2,4-dione 
• 82124-28-5 5-(4-Nitro-phenyl)-thiazolidine-2,4-dione 
• 82124-29-6 5-(4-aminophenyl)thiazolidine-2,4-dione 
• 609339-96-0 α-acetoxy-p-nitrobenzyl carbanion 
• 609339-95-9 tert-butyl hydroxy-(4-nitrophenyl)acetate 
• 609339-99-3 α-hydroxy-p-nitrobenzyl carbanion 
• 555-16-8 4-nitrobenzaldehdye 
• 74663-99-3 4-nitroso-benzaldehyde 
• 10098-39-2 2-hydroxy-2-(4-nitrophenyl)acetic acid 
• 30747-39-8 α,α'-bisacetoxy-p,p'-dinitrobibenzyl 
• 29704-35-6 tert-butyl 2-acetoxy-2-(4-nitrophenyl)acetate 

Relevant academic research and scientific papers

2,7-Diazabicyclo[2.2.1]heptanes: Novel asymmetric access and controlled bridge-opening

Organocatalysed asymmetric Michael additions of substituted triketopiperazines to enones afford products in high yield and enantiomeric ratio (er). Further modification delivers products possessing natural product (NP) scaffolds including diazabicyclo[2.2

Chemistry of photogenerated α-hydroxy-p-nitrobenzyl carbanions in aqueous solution: Protonation vs. disproportionation

The photochemistry of p-nitrobenzyl derivatives 6-10 has been studied in aqueous solution as a function of pH, using product analysis, UV-vis spectrophotometry, and laser flash photolysis (LFP). The compounds were chosen with the aim of further exploring the propensity of these systems to give rise to α-hydroxy-p-nitrobenzyl carbanions on photolysis, and to study their mechanisms of subsequent reaction, α-Hydroxy-substituted carbanions are anions that cannot be readily formed using thermal routes but which are believed to have some interesting chemistry. Three methods were employed for photogenerating these carbanions: (i) decarboxylation; (ii) retro-Aldol reaction; and (iii) carbon acid deprotonation. All three methods proved to be successful using the p-nitrobenzyl chromophore. Photogenerated α-hydroxy-p-nitrobenzyl carbanions react via disproportionation, giving rise to oxidized and reduced products; simple protonation of the anion was undetectable.

1,3-Dipolar Character of Six-membered Aromatic Rings. Part 52. 2?+8? Cycloaddition Reactions of 1-Substituted 3-Oxidopyridinium Betaines

Dichloroketen and a series of aryl(bromo)ketens react with various 1-substituted 3-oxidopyridiniums to give novel bicyclic compounds by addition across the C(4)-O and the C(2)-O positions.Frontier-MO theory is used to rationalise the orientation of these cycloadditions.Acid-catalysed hydrolysis of the C(2)-O adducts (9) yielded 3-hydroxy-2-benzylpyridines.