75288-22-1Relevant academic research and scientific papers
2,7-Diazabicyclo[2.2.1]heptanes: Novel asymmetric access and controlled bridge-opening
Peczkowski, Gary R.,Craven, Philip G. E.,Stead, Darren,Simpkins, Nigel S.
supporting information, p. 4214 - 4217 (2019/05/09)
Organocatalysed asymmetric Michael additions of substituted triketopiperazines to enones afford products in high yield and enantiomeric ratio (er). Further modification delivers products possessing natural product (NP) scaffolds including diazabicyclo[2.2
Attempts to Prepare an Alkynyldiazonium Salt
Helwig, Reinhard,Hanack, Michael
, p. 1008 - 1021 (2007/10/02)
The 2-bromo-1-chloroalkanal p-tosylhydrazones 11a and b react with triethylamine as base to give the azoalkenes 12, of which (1-chloro-2-phenylethenyl)tosyldiazene (12b) is obtained as a crystalline material at room temperature. 12b reacts with SbCl5 at -30 and -70 deg C to form different diazonium salts, which are treated with nucleophiles such as methanol and water.The products obtained (Schemes 3 and 4) indicate the formation of the phenylethenyldiazonium salt 20, which is stable up to -20 deg C. 20 adds nucleophiles like methanol or water as well as anisole at the CC triple bond before releasing nitrogen.
1,3-Dipolar Character of Six-membered Aromatic Rings. Part 52. 2?+8? Cycloaddition Reactions of 1-Substituted 3-Oxidopyridinium Betaines
Katritzky, Alan R.,Cutler, Alan T.,Dennis, Nicolas,Sabongi, Gebran J.,Rahimi-Rastgoo, Soheila,et al.
, p. 1176 - 1184 (2007/10/02)
Dichloroketen and a series of aryl(bromo)ketens react with various 1-substituted 3-oxidopyridiniums to give novel bicyclic compounds by addition across the C(4)-O and the C(2)-O positions.Frontier-MO theory is used to rationalise the orientation of these cycloadditions.Acid-catalysed hydrolysis of the C(2)-O adducts (9) yielded 3-hydroxy-2-benzylpyridines.
