752963-23-8

Basic information

• Product Name: (R)-3-amino-4-(2-chloro-phenyl)-butyric acid ethyl ester
• Synonyms: (R)-3-amino-4-(2-chloro-phenyl)-butyric acid ethyl ester
• CAS NO: 752963-23-8
• Molecular Weight: 241.718
• Mol File: 752963-23-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-3-amino-4-(2-chloro-phenyl)-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-amino-4-(2-chloro-phenyl)-butyric acid ethyl ester(752963-23-8)
• EPA Substance Registry System: (R)-3-amino-4-(2-chloro-phenyl)-butyric acid ethyl ester(752963-23-8)

Safety Data

• Hazardous Substances Data: 752963-23-8(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 268734-28-7 (R)-3-Amino-4-(2-chloro-phenyl)-butyric acid 

Downstream Products

• 1415483-29-2 2-{3-[(R)-1-Carboxymethyl-2-(2-chlorophenyl)-ethylcarbamoyl]-propyl}-benzoic Acid 
• 1429316-51-7 C₁₈H₁₈BrClN₂O₃ 
• 1415312-02-5 2-{2-[(R)-1-carboxymethyl-2-(2-chlorophenyl)ethylcarbamoyl]pyridin-4-yl}benzoic acid trifluoroacetic acid salt 

Relevant articles and documents

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, a, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.