753-72-0Relevant academic research and scientific papers
New General Synthesis of Organophosphorus P-F Compounds via Reaction of Azolides of Phosphorus Acids with Acyl Fluorides: Novel Route to 2-Deoxynucleosidyl Phosphorofluoridates and Phosphorodifluoridates
Dabkowski, Wojciech,Michalski, Jan,Wasiak, Jacek,Cramer, Friedrich
, p. 817 - 820 (2007/10/02)
Tetra- and tri-coordinate P-N-imidazole derivatives and their structural analogous react smoothly with acyl fluorides to give the corresponding P-F compounds an almost quantitative yield.This method has been successfully applied to produce 2-deoxynucleosidyl phosphorofluoridates and phosphorodifluoridates.
ORGANOSILICON AND ORGANOPHOSPHORUS COMPOUNDS WITH PSEUDOHALIDE GROUPS 3. REACTIONS OF ALKOXYDIMETHYLSILYL CYANIDES WITH TETRACOORDINATED PHOSPHORUS HALIDES
Krolevets, A. A.,Antipova, V. V.,Petrovskii, P. V.,Martynov,I. V.
, p. 153 - 157 (2007/10/02)
The reactions of alkoxydimethylsilyl cyanides with some tetracoordinated phosphorus chlorides and fluorides were investigated.It was shown that the investigated reactions are realized primarily with the replacement of two halogen atoms by functional groups.The transformations of the phosphorus acid cyanides obtained with metal fluorides were studied. Keywords: silyl cyanides, phosphorus(IV) halides, substitution reactions, metal fluorides.
A NEW SYNTHESIS OF PHOSPHOROFLUORIDATES OF BIOLOGICAL INTEREST. THE REACTION OF PHOSPHOROAZOLIDES WITH BENZOYL FLUORIDE
Dabkowski, Wojciech,Cramer, Friedrich,Michalski, Jan
, p. 3561 - 3562 (2007/10/02)
Phosphoroazolides, including nucleoside derivatives, can be converted smoothly into the corresponding phosphorofluoridates by reaction with benzoyl fluoride.From these compounds oligonucleotides containing P-F instead of P-OH can be prepared.
