753015-96-2

Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL3-VINYLPYRROLIDINE-1-CARBOXYLATE is used as a building block for the synthesis of various pharmaceuticals due to its ability to contribute to the development of new drugs with improved efficacy and stability.
Used in Agrochemical Industry:
In the agrochemical industry, TERT-BUTYL3-VINYLPYRROLIDINE-1-CARBOXYLATE is utilized as a building block for the synthesis of agrochemicals, potentially enhancing the performance and stability of these products.
Used as a Stabilizer:
TERT-BUTYL3-VINYLPYRROLIDINE-1-CARBOXYLATE is used as a stabilizer in some formulations to improve the shelf life and performance of the final product.
Used in Research and Development:
TERT-BUTYL3-VINYLPYRROLIDINE-1-CARBOXYLATE is a potential precursor for the preparation of biologically active compounds and is under ongoing research for its potential use in the development of innovative drugs and agrochemical products, indicating its importance in advancing scientific discovery and application.

Upstream product

• 59379-02-1 tert-butyl 3-formylpyrrolidine-1-carboxylate 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Relevant academic research and scientific papers

THERAPEUTIC METHODS

The invention provides methods and compositions for delivering a nucleic acid to a cell or the cytosol of the target cell. The method includes contacting the cell with, 1) a membrane-destabilizing polymer; and 2) a nucleic acid conjugate. The nucleic acid conjugate includes a targeting ligand bound to an optional linker and a nucleic acid.

TARGETED COMPOSITIONS

The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).

Polysubstituted-indazole compounds and application of same as IDO inhibitors

The invention discloses polysubstituted-indazole compounds as shown in a formula (I) which is described in the specification, a preparation method for the compounds, and application of the compounds as IDO inhibitors. The compounds provided by the invention can be used for preventing and/or treating a plurality of diseases, such as Alzheimer's disease, cataract, infections related to cellular immune activation, autoimmune diseases, AIDS, cancers, depression, the metabolic disorder of tryptophan or the like.

ARYL-SUBSTITUTED HETEROCYCLIC UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE

Certain aryl-substituted heterocyclic urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis).

Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Novel vinylazacycloalkane compounds of Formula (I) are disclosed. The compounds are ligands of various nAChRs. The compounds and their pharmaceutically acceptable salts can be used to prepare pharmaceutical compositions and/or medicaments intended to prevent or treat disorders associated with dysfunction of nAChRs, especially within the central nervous system or the gastrointestinal system. Examples of types of disorders that can be treated include neurodegenerative disorders, including central nervous system disorders such as Alzheimer's disease, cognitive disorders, motor disorders such as Parkinson's disease, drug addiction, behavioral disorders and inflammatory disorders within the gastrointestinal system. The compounds can also serve as analgesics in the treatment of acute, chronic or recurrent pain.