75302-66-8Relevant academic research and scientific papers
Selective synthesis of chlorophosphoramidites using ionic liquids
Amigues, Eric J.,Hardacre, Christopher,Keane, Gillian,Migaud, Marie E.,Norman, Sarah E.,Pitner, William R.
scheme or table, p. 1391 - 1396 (2010/05/18)
A range of chlorophosphoramidites have been prepared in ionic liquids and compared with material synthesised in molecular solvents. Through the use of ionic liquids as reaction media the moisture sensitivity and impurity issues hampering existing traditio
Nitrobenzyl Phosphorodiamidates as Potential Hypoxia-Selective Alkylating Agents
Mulcahy, R. Timothy,Gipp, Jerry J.,Schmidt, James P.,Joswig, Carolyn,Borch, Richard F.
, p. 1610 - 1615 (2007/10/02)
A series of novel nitrobenzyltetrakis(chloroethyl)phosphorodiamidates has been prepared, and its cytotoxicity has been evaluated against HT-29 cells under aerobic and hypoxic conditions and against murine bone marrow progenitor cells under aerobic conditi
DEOXYRIBONUCLEOSIDE 3'-PHOSPHORDIAMIDITES AS SUBSTRATES FOR SOLID SUPPORTED SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES AND THEIR PHOSPHOROTHIOATE AND DNA-TRIESTER ANALOGUES
Uznanski, Bogdan,Wilk, Andrzej,Stec, Wojciech J.
, p. 3401 - 3404 (2007/10/02)
5'-O-Dimethoxytrityl-base protected-nucleoside 3'-O-phosphordimorpholidites can be successfully used for the synthesis of oligodeoxyribonucleotides and their phosphorothioate or "triester" analogues.
AMIDATION OF HALOGEN DERIVATIVES OF PHOSPHORUS WITH 4,4',4''-METHYLIDYNETRISMORPHOLINE
Shevchenko, M. V.,Kukhar', V. P.
, p. 1336 - 1340 (2007/10/02)
4,4'4''-Methylidynetrismorpholine amidates polyhalophosphorus compounds and is a more reactive agent than the previously studied N,N,N'N'-tetraalkylmethanediamines.The dimorpholinomethylium chloride formed as a result of the reaction does not react with the amidation products, which makes it possible to isolate them in a pure state.
