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FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID, with the molecular formula C18H19NO4S, is a chemical compound derived from thiazolidine-4-carboxylic acid. It is recognized for its role as a chiral auxiliary in organic synthesis, where it imparts chirality to molecules it is attached to. The FMOC (9-fluorenylmethoxycarbonyl) group on the compound provides protection to the carboxylic acid functionality, enabling selective deprotection and modification. FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID is instrumental in the synthesis of complex organic molecules, particularly in the production of peptides and other organic molecules, making it a valuable asset in organic chemistry.

753030-79-4

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753030-79-4 Usage

Uses

Used in Organic Synthesis:
FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID is used as a chiral auxiliary for imparting chirality to organic molecules, which is crucial for the synthesis of enantiomerically pure compounds. This is particularly important in pharmaceuticals, where the chirality of a molecule can significantly affect its biological activity and efficacy.
Used in Peptide Synthesis:
In the field of peptide synthesis, FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID is used as a building block. Its ability to protect the carboxylic acid functionality allows for the stepwise assembly of peptide chains with controlled selectivity, facilitating the synthesis of complex peptide structures.
Used in Pharmaceutical Industry:
FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID is used as a key intermediate in the development of pharmaceutical compounds. Its role in creating enantiomerically pure drugs ensures that the synthesized compounds have the desired biological activity and minimize potential side effects associated with the presence of unwanted enantiomers.
Used in Research and Development:
In academic and industrial research settings, FMOC-(R)-5,5-DIMETHYLTHIAZOLIDINE-4-CARBOXYLIC ACID is utilized for the exploration of new synthetic routes and methodologies. Its unique properties make it a valuable tool for studying the effects of chirality on molecular interactions and reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 753030-79-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,3,0,3 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 753030-79:
(8*7)+(7*5)+(6*3)+(5*0)+(4*3)+(3*0)+(2*7)+(1*9)=144
144 % 10 = 4
So 753030-79-4 is a valid CAS Registry Number.

753030-79-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:753030-79-4 SDS

753030-79-4Relevant academic research and scientific papers

Highly Potent and Selective Heptapeptide Antagonists of the Neurokinin NK-2 Receptor

McElroy, Andrew B.,Clegg, Stephen P.,Deal, Martyn J.,Ewan, Georg B.,Hagan, Russell M.,et al.

, p. 2582 - 2591 (2007/10/02)

Incorporation of D-Pro9 into substance P related peptides is known to enhance neurokinin NK-2 receptor agonist potency and selectivity with respect to other neurokinin receptors.We now report that replacement of D-Trp9 by D-Pro9

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