75304-21-1

Upstream product

• 95-51-2 o-chloroaniline 
• 123-54-6 acetylacetone 

Downstream Products

• 1239368-72-9 C₂₈H₂₁ClN₈ 
• 1310823-87-0 1-(6-chlorobenzothiazol-2-yl)-3,5-dimethyl-4-(2-chlorophenylazo)pyrazole 
• 135033-79-3 3-[4-(2-Chloro-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-3-oxo-N-p-tolyl-propionamide 
• 135033-81-7 N-(2-Chloro-phenyl)-3-[4-(2-chloro-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-3-oxo-propionamide 
• 135033-80-6 3-[4-(2-Chloro-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-N-(2-methoxy-phenyl)-3-oxo-propionamide 
• 98077-63-5 [4-(2-Chloro-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-pyridin-2-yl-methanone 
• 135033-82-8 N-(4-Chloro-phenyl)-3-[4-(2-chloro-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-3-oxo-propionamide 
• 135033-78-2 1-(anilinomalonyl)-3,5-dimethyl-4-(o-chlorophenylazo)pyrazole 
• 126440-72-0 C₁₈H₁₅ClN₄O₂ 
• 1398415-35-4 1-[3-methyl-2-(2-chlorophenyldiazenyl)-2H-aziren-2-yl]ethanone 
• 1398415-04-7 C₁₁H₁₂ClN₃O₂ 

Relevant academic research and scientific papers

Evaluation of Substituent Effect in Z -Isomer Stability of Arylazo-1 H -3,5-dimethylpyrazoles: Interplay of Steric, Electronic Effects and Hydrogen Bonding

The electronic and steric effects of aryl substituents and the influence of hydrogen bonding in Z-isomer stability of phenylazopyrazole derivatives have been investigated. In this regard, 38 substituted phenylazopyrazole derivatives and 6 N-methyl phenyla

Synthesis and QSAR modeling 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl] ethanones as potential antibacterial agents

The present communication deals with the synthesis of a series of 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl]ethanones. The compounds were synthesized in excellent yields (70-80 %), and the structures were established on the basis of consistent IR, 1H NMR, and elemental analysis data. The purity has been ascertained by chromatographic resolution using hexane-ethyl acetate (6:4 v/v) as binary eluent. All the compounds have been tested for their antimicrobial activity against a representative panel of bacteria i.e., Bacillus subtilis, Escherichia coli, Pseudomonas diminuta, and Staphylococcus aureus using Chloramphenicol as reference drug. All the synthesized compounds were found to exhibit profound antimicrobial activity.

Synthesis and antimicrobial activity of pyrazolinones and pyrazoles having benzothiazole moiety

A new class of 4-arylhydrazono-1-benzothiazolyl-3-methylpyrazolin-5-ones (3a-j) and 4-arylazo-1-benzothiazolyl-3,5-dimethylpyrazoles (4a-j) were designed as pharmacophore hybrids between pyrazolinone/pyrazole and benzothiazole moiety. The target molecules were efficiently synthesized by the cyclization of various oxobutyrates/pentane-2,4-dione derivatives with 6-chloro-2- hydrazinobenzothiazole in the presence of glacial acetic acid. The compounds were evaluated for their in vitro antimicrobial activity. Preliminary study of the structure-activity relationship revealed that electron-withdrawing groups in phenyl ring had a promising effect on the antimicrobial activity. Also, correlation study has been used to establish the relationships between the antibacterial activity and physicochemical parameter clogP. Springer Science+Business Media, LLC 2011.

Pyridazine derivatives and related compounds. 23*. synthesis of 3-substituted pyrazolo[3,4-c] pyridazines and their application as disperse dyes

Acetylacetone and malononitrile were coupled with diazotized arylamines to give arylazoacetylacetones and arylazomalononitriles. When refluxed with 3-hydrazino-4,5-diphenyl-1H-pyrazolo-[3,4-c]pyridazine in the presence of ethanol/HCl, they yielded the corresponding 3-[4-(arylazo)-3,5-dimethylpyrazol- 1-yl]- and 3-[3,5-diamino-4-(arylazo)pyrazol-1-yl]-4,5-diphenyl-1H-pyrazolo[3,4- c]pyridazine dyes. The dyes were applied to polyester and polyamide fabrics, and their spectral and fastness properties were measured.