75318-35-3Relevant academic research and scientific papers
Synthesis, structural revision, and biological activities of 4′-chloroaurone, a metabolite of marine brown alga Spatoglossum variabile
Venkateswarlu, Somepalli,Panchagnula, Gopala K.,Gottumukkala, Aditya L.,Subbaraju, Gottumukkala V.
, p. 6909 - 6914 (2007)
4′-Chloroaurone (1a), the only aurone reported from a marine source, Spatoglossum variabile was synthesized from 2-hydroxyacetophenone along with six structural analogs. The products obtained were Z-isomers and these were converted into E-isomers by photo
Construction of the flavones and aurones through regioselective carbonylative annulation of 2-bromophenols and terminal alkynes
Liu, Jianming,Liu, Muwen,Yue, Yuanyuan,Zhang, Ningfei,Zhang, Yuanli,Zhuo, Kelei
supporting information, p. 1802 - 1807 (2013/04/24)
The easily available and efficient catalyst containing a benzimidazolium ligand and PdCl2(PPh3)2 demonstrated excellent catalytic activity to construct the flavones and aurones, respectively. This reaction can be operated under mild conditions, affording the desired products in moderate to good yields. This protocol was used to prepare the flavones and aurones by a slight modification of amines.
FLAVONOIDS, XXXVI REACTION OF 3-ALKYL- OR -ARYLSULFONYLOXYFLAVANONES WITH AMINES. SYNTHESIS OF 3-DIALKYLAMINOFLAVANONES
Patonay, T.,Litkei, Gy.,Bognar, R.
, p. 135 - 146 (2007/10/02)
Reactions of 3-alkyl- or -arylsulfonyloxyflavanones (1a-h) with primary and tertiary amines gave mixtures of the corresponding flavones (2a-d) and aurones (3a-d), while with secondary amines, in addition to 2 and 3, 3-dialkylaminoflavanones (6-9) were also obtained.The factors which determine the ratio of products are discussed.Treatment of the 3-dialkylaminoflavones 6a and 7 with DDQ gave 3-dialkylaminoflavanones (10, 11); treatment with alkali in methanol afforded 2-dialkylamino-2-benzylcoumaran-3-ones (12, 13).
