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2-Chloroethyl ethyl phenylphosphonate is an organophosphorus compound with the chemical formula C10H14ClO3P. It is a colorless liquid that is soluble in organic solvents. 2-chloroethyl ethyl phenylphosphonate is primarily used as a chemical warfare agent, specifically as a nerve agent. It inhibits the enzyme acetylcholinesterase, which is crucial for the proper functioning of the nervous system. By blocking this enzyme, it leads to the accumulation of acetylcholine, causing overstimulation of muscles and nerves, ultimately leading to respiratory failure and death. Due to its toxicity and potential for misuse, the production and stockpiling of 2-chloroethyl ethyl phenylphosphonate are strictly regulated under international law, such as the Chemical Weapons Convention.

7533-70-2

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7533-70-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7533-70-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,3 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7533-70:
(6*7)+(5*5)+(4*3)+(3*3)+(2*7)+(1*0)=102
102 % 10 = 2
So 7533-70-2 is a valid CAS Registry Number.

7533-70-2Downstream Products

7533-70-2Relevant academic research and scientific papers

Direct Aryloxylation/Alkyloxylation of Dialkyl Phosphonates for the Synthesis of Mixed Phosphonates

Huang, Hai,Denne, Johanna,Yang, Chou-Hsun,Wang, Haobin,Kang, Jun Yong

, p. 6624 - 6628 (2018)

A strategy for the direct functionalization strategy of inertial dialkyl phosphonates with hydroxy compounds to afford diverse mixed phosphonates with good yields and functional-group tolerance has been developed. Mechanistic investigations involving both NMR studies and DFT studies suggest that an unprecedented highly reactive PV species (phosphoryl pyridin-1-ium salt), a key intermediate for this new synthetic transformation, is generated in situ from dialkyl phosphonate in the presence of Tf2O/pyridine.

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