75340-01-1Relevant academic research and scientific papers
Synthesis of 5,7-Dihydroxy-2',4',5'-trimethoxyisoflavone and Its 7-Methyl Ether (Robustigenin)
Nakayama, Mitsuru,Ohira, Susumu,Matsui, Takanao
, p. 831 - 832 (2007/10/02)
The treatment of 2,4,6-trihydroxy-2',4',5'-trimethoxydeoxybenzoin with benzyl chloride gave a dibenzyl ether.The condensation of the ether with ethyl formate, followed by the debenzylation of the resulting isoflavone, afforded 5,7-dihydroxy-2',4',5'-trimethoxyisoflavone, which was then converted into a pentamethoxyisoflavone.The partial demethylation of the pentamethoxyisoflavone gave 5-hydroxy-2',4',5',7'-tetramethoxyisoflavone, which was identical with natural robustigenin.
