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753433-10-2

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753433-10-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 753433-10-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,3,4,3 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 753433-10:
(8*7)+(7*5)+(6*3)+(5*4)+(4*3)+(3*3)+(2*1)+(1*0)=152
152 % 10 = 2
So 753433-10-2 is a valid CAS Registry Number.

753433-10-2Upstream product

753433-10-2Relevant academic research and scientific papers

Novel echinocandin antifungals. Part 2: Optimization of the side chain of the natural product FR901379. Discovery of micafungin

Tomishima, Masaki,Ohki, Hidenori,Yamada, Akira,Maki, Katsuyuki,Ikeda, Fumiaki

, p. 2886 - 2890 (2008/12/23)

Further optimization of the potent antifungal activity of side chain analogs of the natural product FR901379 led to the discovery of compound 8 with an excellent, well-balanced profile. Potent compounds with reduced hemolytic potential were designed based upon a disruption of the linearity of the terphenyl lipophilic side chain. The optimized compound (8, FK463, micafungin) displayed the best balance and was selected as the clinical candidate.

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