7535-57-1

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 95-95-4 2,4,5-trichlorophenol 
• 108034-67-9 1,2,2,2-tetrachloroethyl 2,4,5-trichlorophenyl carbonate 

Downstream Products

• 1226758-61-7 Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,ζ-diaminohexanol 
• 1226758-59-3 Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,δ-diaminobutanol 
• 1226758-58-2 Nα,N',Nα,N'-tetrakis(3-(Boc-L-phenylalanylamino)propyl)-L-β,γ-diaminopropanol 

Relevant academic research and scientific papers

Novel Preparation of N-Protected Amino Acid Active Esters Using 1,2,2,2-Tetrachloroethyl Carbonates

1,2,2,2-Tetrachloroethyl chloroformate reacts with substituted phenols or N-hydroxy imides to yield crystalline and stable mixed aryl or oximido tetrachloroethyl carbonates.When allowed to react with an N-protected amino acid derivative, these compounds proved to be efficient for the syntheses of the corresponding active esters.A series of active esters including p-nitrophenol, trichlorophenol, pentafluorophenol, and N-hydroxysuccinimide derivatives were prepared by this new procedure.