7535-87-7Relevant academic research and scientific papers
Cyclizing pentapeptides: Mechanism and application of dehydrophenylalanine as a traceless turn-inducer
Le, Diane N.,Riedel, Jan,Kozlyuk, Natalia,Martin, Rachel W.,Dong, Vy M.
, p. 114 - 117 (2017/11/27)
Dehydrophenylalanine is used as a traceless turn-inducer in the total synthesis of dichotomin E. Macrocyclization of the monomer is achieved in high yields and selectivity over cyclodimerization under conditions 100 times more concentrated than previously achieved. The enamide facilitates ring closing, and Rh-catalyzed hydrogenation of the unsaturated cyclic peptide results in selective formation of the natural product or its epimer, depending on our choice of phosphine ligand. NMR analysis and molecular modeling revealed that the linear peptide adopts a left-handed α-turn that preorganizes the N- and C-termini toward macrocyclization.
Smart oligopeptide gels: In situ formation and stabilization of gold and silver nanoparticles within supramolecular organogel networks
Ray, Sudipta,Das, Apurba Kumar,Banerjee, Arindam
, p. 2816 - 2818 (2008/09/19)
Tripeptide with redox active chemical entities based smart organogels have been used for in situ formation and stabilization of gold and silver nanoparticles within the supramolecular gel networks and the gold nanoparticles are aligned in arrays along the gel nanofibers of peptide 1-toluene gels. The Royal Society of Chemistry 2006.
SEGMENT COUPLING IN PEPTIDE SYTHESIS-II A SIMPLE PREDICTIVE EQUATION CORRELATING RACEMIZATION AND PRIMARY STRUCTURE
Nguyen, Dung Le,Dormoy, Jean-Robert,Castro, Bertrand,Prevot, Daniel
, p. 4229 - 4238 (2007/10/02)
A predictive equation based on extrathermodynamic assumptions is proposed, that allows the prediction of the degree of epimerization in tripeptide model reactions of condensation of peptide segments as a function of the primary structure.The experimental
