75378-61-9Relevant academic research and scientific papers
Copper-catalyzed intramolecular dehydrogenative aminooxygenation: Direct access to formyl-substituted aromatic N-heterocycles
Wang, Honggen,Wang, Yong,Liang, Dongdong,Liu, Lanying,Zhang, Jiancun,Zhu, Qiang
supporting information; experimental part, p. 5678 - 5681 (2011/08/02)
A direct synthesis of carbaldehydes through intramolecular dehydrogenative aminooxygenation has been developed. The process uses a catalytic amount of copper(II) in DMF or DMA under oxygen and does not require additional oxidants (see scheme). Mechanistic studies suggest that the carbonyl oxygen atom of the aldehyde is derived from oxygen through a copper-mediated oxygen activation process via a peroxy-copper(III) intermediate. Copyright
Novel Pyrimidine Rearrangement Reaction. A New Synthesis of 4-Formylimidazoles
Goenczi, C.,Swistun, Z.,Plas, H. C. van der
, p. 608 - 610 (2007/10/02)
5-Aminopyrimidine gives, on mild heating with N-alkyl(aryl)imidoyl chlorides in the presence of phosphorus oxychloride, 4-formyl-1,2-dialkyl(aryl)imidazoles together with the N-(pyrimidin-5-yl)-N-alkyl(aryl)amidines.It was found that these amidines are th
