75381-39-4Relevant academic research and scientific papers
Structural study-guided development of versatile phase-transfer catalysts for asymmetric conjugate additions of cyanide
Provencher, Brian A.,Bartelson, Keith J.,Liu, Yan,Foxman, Bruce M.,Deng, Li
, p. 10565 - 10569 (2011/12/05)
Unprecedented phase-transfer catalysts for the first example of an organocatalytic asymmetric conjugate addition of cyanide with acetone cyanohydrin are reported (see scheme). Utilizing an accessible cupreidinium salt and a cyanation reagent suitable for industrial scale, this reaction holds significant promise for practical asymmetric synthesis. The catalysts were developed as a result of key structural insights gained by X-ray analysis. Copyright
SUBSTITUTED THIO-SUBSTITUTED BENZYL-PROPIONYL-L-PROLINES
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, (2008/06/13)
This disclosure describes novel substituted ω-aroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.
