75388-78-2

Upstream product

• 74-96-4 ethyl bromide 
• 80898-80-2 4-Nitrobenzyl 7-oxo-3-thioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 69077-79-8 2-[(4R,S)-ethylthiothiocarbonylthio-2-oxo-1-azetidinyl]-2-hydroxyacetic acid p-nitrobenzyl ester 
• 69077-80-1 Chloro-(2-ethylsulfanylthiocarbonylsulfanyl-4-oxo-azetidin-1-yl)-acetic acid 4-nitro-benzyl ester 
• 75388-67-9 ethyl 2-oxo-azetidin-4-yl trithiocarbonate 
• 75401-07-9 ethyl trithiocarbonate 

Relevant academic research and scientific papers

7-Oxo-4-thia-1-aza[3,2,0]heptane and 7-oxo-4-thia-1-aza[3,2,0]hept-2-ene derivatives

What are disclosed are compounds, useful as intermediates in the preparation of substituted penem compounds, of the formula STR1 methods for making such compounds from intermediates of the formula STR2 by reaction of the latter with a nucleophilic compound, methods for making such intermediates from compounds of the formula STR3 by reaction of the last-mentioned compounds with a tervalent phosphorus compound, and methods for making said last-mentioned compounds by cyclizing compounds of the formula STR4 with a tervalent phosphorus compound.