7541-03-9Relevant academic research and scientific papers
Copper-Catalyzed Carbonyl Group Controlled Coupling of Isatin Oximes with Arylboronic Acids To Prepare N-Aryloxindole Nitrones
Mo, Xue-Ling,Chen, Chun-Hua,Liang, Cui,Mo, Dong-Liang
, p. 150 - 159 (2017/11/28)
A variety of (E)-N-aryloxindole nitrones were prepared in good to excellent yields by using a copper-catalyzed coupling reaction of isatin oximes and arylboronic acids under mild conditions. Various arylboronic acids that contain sensitive functional groups were tolerated in the transformation, and detailed studies show that the carbonyl group of the isatin oximes serves as a ligand to control the formation of the (E)-oxindole nitrones. This method to prepare (E)-N-aryloxindole nitrones was easily performed on a gram scale and efficiently used to synthesize estrone-derived oxindole nitrone in high yield.
E/Z oxime isomerism in PhC(NOH)CN
Bohle, D. Scott,Chua, Zhijie,Perepichka, Inna,Rosadiuk, Kristopher
, p. 4223 - 4229 (2013/05/09)
The reaction of nitric oxide with benzyl cyanide in the presence of potassium methoxide at low temperature gave the dipotassium salt of a bis-diazeniumdiolate 2 in excellent yield. Two new stereospecific syntheses of E or Z 2-(hydroxyimino)-2-phenylacetonitrile from 2 have been found. The thermodynamics of the E/Z isomerization has been investigated spectroscopically in solution, in the solid state by differential scanning calorimetry (DSC), and theoretically in the gas phase. Evidence of catalysis by NO of E/Z oxime isomerization has been observed. Copyright
Stereoselective Synthesis of (E)-2-Hydroxyimino-2-phenylacetonitrile by Photolysis of 4-Azido-3-phenylfurazan 2-Oxide
Kunai, Atsutaka,Doi, Takanori,Nagaoka, Takashi,Yagi, Hirofumi,Sasaki, Kazuo
, p. 1843 - 1844 (2007/10/02)
Synthesis of (E)-2-hydroxyimino-2-phenylacetonitrile from styrene was examined.This compound was obtained selectively by the photolysis of 4-azido-3-phenylfurazan 2-oxide.
Oxime sulfonates containing reactive groups
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, (2008/06/13)
Oxime sulfonates of formula I STR1 wherein Y is a polymerizable unsaturated group or epoxide group or an --OH, --NHR5, --COOH, COOR6, --COCl, --CH2 Hal, --SO2 Cl or --NCO group, Z is an (x+y)-valent connecting member, R1 and R2 are monovalent organic radicals, m is 0 or 1, x is 1 or 2 and y is 1 or 2, can be converted into polymers which can be thermally or photochemically dissociated to form free sulfonic acid groups. Said polymers can therefore be used as photoresists which can be developed with aqueous alkalis.
Process for preparing α-ketocarboxylic acids
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, (2008/06/13)
A novel process for the manufacture of α-ketocarboxylic acids which comprises the reaction of oximinohalide with cyanide ion to form oximinonitrile which is reacted with hydroxide ion to form oximinoacid and hydrolysis thereof to the α-ketoacid.
Process for the preparation of oximinonitriles
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, (2008/06/13)
A novel process for the manufacture of oximinonitriles which comprises the reaction of an oximinohalide with cyanide ion.
Process for the preparation of 2-oxoiminophenylacetonitrile
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, (2008/06/13)
In the preparation of 2-oximinophenylacetonitrile by reacting benzyl cyanide with an alkyl nitrite in the presence of a base, the improvement which comprises employing an inorganic base as the base and effecting the reaction in an aqueous solution of an a
