754190-28-8 Usage
Description
(3-bromophenyl)(4,6-dichloropyrimidin-5-yl)methanone, also known as C12H6BrCl2N3O, is a chemical compound that features a ketone group with a bromophenyl group and a 4,6-dichloropyrimidin-5-yl group attached to the carbonyl carbon. This versatile intermediate is a white to off-white solid and is widely used in the synthesis of various biologically active molecules and agrochemicals.
Uses
Used in Pharmaceutical Industry:
(3-bromophenyl)(4,6-dichloropyrimidin-5-yl)methanone is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a range of biologically active molecules that can be utilized in the development of new drugs and therapies.
Used in Agricultural Industry:
In the agricultural sector, (3-bromophenyl)(4,6-dichloropyrimidin-5-yl)methanone serves as a key intermediate in the production of various agrochemicals. Its incorporation into these compounds can lead to the development of more effective pesticides, herbicides, and other agricultural products that help improve crop yields and protect against pests and diseases.
As with any chemical compound, it is crucial to follow proper handling and safety precautions when working with (3-bromophenyl)(4,6-dichloropyrimidin-5-yl)methanone to ensure the safety of both the individuals involved and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 754190-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,4,1,9 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 754190-28:
(8*7)+(7*5)+(6*4)+(5*1)+(4*9)+(3*0)+(2*2)+(1*8)=168
168 % 10 = 8
So 754190-28-8 is a valid CAS Registry Number.
754190-28-8Relevant articles and documents
Synthesis and biological evaluation of pteridine and pyrazolopyrimidine based adenosine kinase inhibitors
Gomtsyan, Arthur,Didomenico, Stanley,Lee, Chih-Hung,Stewart, Andrew O.,Bhagwat, Shripad S.,Kowaluk, Elizabeth A.,Jarvis, Michael F.
, p. 4165 - 4168 (2007/10/03)
Three new approaches have been tested to modify existing pyridopyrimidine and alkynylpyrimidine classes of nonnucleoside adenosine kinase inhibitors 2 and 3. 4-Amino-substituted pteridines 8a-e were generally less active than corresponding 5- and 6-substituted pyridopyrimidines 2. Pyrazolopyrimidine 13c with IC50=7.5nM was superior to its open chain alkynylpyrimidine analog 13g (IC50=22nM) while pyrrolopyrimidines such as 17a were inactive.
