7542-84-9Relevant academic research and scientific papers
Palladium-assisted multicomponent cyclization of aromatic aldehydes, arylamines and terminal olefins under molecular oxygen: An assembly of 1,4-dihydropyridines
Jiang, Huanfeng,Ji, Xiaochen,Li, Yibiao,Chen, Zhengwang,Wang, Azhong
body text, p. 5358 - 5361 (2011/09/13)
The palladium-assisted one-pot three-component reactions of aldehydes, amines and olefins proceeded smoothly to give 2,6-unsubstituted 1,4-dihydropyridines (1,4-DHPs) using molecular oxygen as a sole oxidant. It also provides efficient Pd-catalyzed aerobic oxidation access to the anti-Markovnikov oxidative amination products of olefins from primary aromatic amines and alkenes. The method is atom-efficient, using cheap and easily available starting materials and an environmentally benign oxidant.
Solvent-free synthesis of enamines from alkyl esters of propiolic or but-2-yne dicarboxylic acid in a ball mill
Thorwirth, Rico,Stolle, Achim
supporting information; experimental part, p. 2200 - 2202 (2011/11/06)
A solvent-free method for the addition of amines to dialkylacetylendicarboxylates or alkylpropiolates using a planetary ball mill was developed. Conversion of educts was quantitative within five minutes without use of any catalyst or base. Beside the E-/Z
Formation of 1,2-dihydroquinoline-3-carboxylic acid derivatives from methyl 3-(arylamino)acrylates with hydrogen iodide
Matsumoto, Shoji,Mori, Takahiro,Akazome, Motohiro
experimental part, p. 3615 - 3622 (2010/12/20)
The reaction of methyl 3-(arylamino)acrylates with hydrogen iodide gave 1,2-dihydroquinoline-3-carboxylic acid derivatives at room temperature. This reaction proceeds efficiently in alcoholic solvent; bulky tert-butyl alcohol is the best solvent to give t
