7542-94-1

Basic information

• Product Name: 2-Butenedioic acid, 2-amino-, dimethyl ester, (Z)-
• CAS NO: 7542-94-1
• Molecular Formula: C6H9NO4
• Molecular Weight: 159.142
• Mol File: 7542-94-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butenedioic acid, 2-amino-, dimethyl ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenedioic acid, 2-amino-, dimethyl ester, (Z)-(7542-94-1)
• EPA Substance Registry System: 2-Butenedioic acid, 2-amino-, dimethyl ester, (Z)-(7542-94-1)

Safety Data

• Hazardous Substances Data: 7542-94-1(Hazardous Substances Data)

Upstream product

• 36744-90-8 S,S-Diphenylsulfilimine 
• 624-49-7 dimethylfumarate 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 

Downstream Products

• 23920-83-4 amino-[(toluene-4-sulfonyl)-thiocarbamoyl]-butenedioic acid dimethyl ester 
• 57289-64-2 N-α-acetyl-L-aspartic acid α,β-dimethylester 
• 114249-52-4 (R)-dimethyl 2-acetamidosuccinate 
• 23889-64-7 5-(toluene-4-sulfonylamino)-isothiazole-3,4-dicarboxylic acid dimethyl ester 
• 131022-14-5 3-Amino-6-benzoyloxy-4-methoxycarbonyl-2H-1-benzopyran-2-one 
• 132733-24-5 3-Amino-6-benzoyloxy-4-methoxycarbonyl-2H-naphtho<1,2-b>pyran-2-one 

Relevant articles and documents

ONE STEP SYNTHESIS OF AZIRIDINES BY THE MICHAEL TYPE ADDITION OF FREE SULFIMIDES

The Michael type additions of diphenyl N-unsubstituted sulfimide (free sulfimide) to various electrophilic olefins were carried out.The reaction with cis- and trans-dibenzoylethylene, dimethylfumarate, dimethylmaleate, benzalacetophenone and benzalacetone gave mainly the corresponding trans-2-acylaziridines and trans-enaminoketones.However, phenyl vinyl sulfone or acrylonitrile afforded not the corresponding aziridine but diphenyl-N-2-cyano or N-2-phenylsulfonylethylsulfimide, a simple Michael adduct.When optically active (+)-(R)-o-methoxyphenylphenyl free sulfimide was treated with such an α,β-unsaturated carbonyl compound as benzalacetophenone, an optically active 2-acylaziridine, i.e., (-)-trans-2-benzoyl-3-phenylaziridine was obtained in ca 30percent optical purity and its absolute configuration was assigned as (2R,3S) upon chemical transformation to the configurationally known 2-phenyl-2-benzoylamino-1-ethanol or by comparing its CD spectrum with that of (1R,2R)-1-phenyl-2-benzoyl-cyclopropane.Meanwhile, (-)-(S)-o-methoxyphenylphenyl free sulfimide was found to react with benzalacetophenone to afford (+)-trans-2-benzoyl-3-phenylaziridine of 25percent optical purity.Effects of solvent and temperature on both the distribution of the products ratio and the optical yield were examined.