Basic information

Product Name: 1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione
Synonyms:
CAS NO:75436-69-0
Molecular Formula: C₁₄H₁₆ClNO₃
Molecular Weight: 281.7347
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: 461.7°C at 760 mmHg
Flash Point: 233°C
Appearance: N/A
Density: 1.237g/cm³
Vapor Pressure: 1.05E-08mmHg at 25°C
Refractive Index: 1.546
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione(CAS DataBase Reference)
NIST Chemistry Reference: 1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione(75436-69-0)
EPA Substance Registry System: 1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione(75436-69-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 75436-69-0(Hazardous Substances Data)

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Usage
SDS
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75436-69-0 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione is used as an anticancer agent for the treatment of multiple myeloma, a type of blood cancer. As a prodrug, melflufen is designed to deliver a toxic payload directly to cancer cells, leading to their destruction. Preclinical and clinical trials have shown promising results, making melflufen a candidate for further development in cancer treatment.
Additionally, melflufen may be used in the development of novel drug delivery systems to enhance its applications and efficacy against cancer cells. Various organic and metallic nanoparticles could be employed as carriers for melflufen delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 75436-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,3 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75436-69:
(7*7)+(6*5)+(5*4)+(4*3)+(3*6)+(2*6)+(1*9)=150
150 % 10 = 0
So 75436-69-0 is a valid CAS Registry Number.

75436-69-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-(2-chloroethyl)-4-(4-methoxyphenyl)piperidine-2,6-dione

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75436-69-0 SDS

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75436-69-0Downstream Products

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