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The chemical compound "6-(1,3-dihydroxybutyl)-7-methyl-3-methylidene-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one" is a complex organic molecule with a unique structure. It features a cyclohepta[b]furan-2-one core, which is a seven-membered ring with a furan ring fused to it. The molecule has a 3-methylidene group, indicating the presence of a double bond between carbons 3 and 4, and a methyl group at the 7-position. Additionally, it has a 1,3-dihydroxybutyl chain attached at the 6-position, which contributes two hydroxyl groups and a butyl chain to the molecule. 6-(1,3-dihydroxybutyl)-7-methyl-3-methylidene-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one is characterized by its hexahydro nature, meaning it contains six hydrogen atoms in a cyclic structure, and the presence of a 2H-cyclohepta[b]furan-2-one ring system. The specific arrangement of these functional groups and the ring system give 6-(1,3-dihydroxybutyl)-7-methyl-3-methylidene-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one its distinct chemical properties and potential applications in various fields, such as pharmaceuticals or materials science.

7544-65-2

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7544-65-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7544-65-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,4 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7544-65:
(6*7)+(5*5)+(4*4)+(3*4)+(2*6)+(1*5)=112
112 % 10 = 2
So 7544-65-2 is a valid CAS Registry Number.

7544-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(1,3-dihydroxybutyl)-7-methyl-3-methylidene-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-2-one

1.2 Other means of identification

Product number -
Other names IVALBIN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7544-65-2 SDS

7544-65-2Upstream product

7544-65-2Downstream Products

7544-65-2Relevant academic research and scientific papers

Isolation of isoxanthanol and synthesis of novel derivatives as potential cytotoxic agents

Chinthakindi, Praveen K.,Rath, Santosh K.,Singh, Jasvinder,Singh, Shashank,Koul, Surrinder,Sangwan, Payare L.

, p. 2499 - 2513 (2017)

Abstract: Novel synthetic derivatives of sesquiterpene lactone isoxanthanol (1) have been prepared and bioevaluated against four human cancer cell lines viz. T98G (glioblastoma), A431 (epidermoid carcinoma), NCI-H322 (bronchioloalveolar carcinoma), and A549 (lung adeno carcinoma) for their cytotoxic potential using paclitaxel as the standard. This has resulted in the identification of potent molecules displaying IC50 1.9 and 5.0 μM, respectively against the A549 cancer cell line. The study has resulted in the identification of potential cytotoxic activity of the analog (compound 10) bearing electron donating aryl alkenoic substituent. Furthermore, the induction of cell death has been assessed for the most active compound (10) using flow cytometric method and sub-G1 cell population determination by propidium iodide staining. The concentration dependent inhibitory effect of 10 on the A549 cells ability did not reproduce and form colonies at 20 μM concentration. Graphical Abstract: Synthesis of isoxanthanol derivatives and their cytotoxic study resulted in identification of potential cytotoxic agents. Compound 10, one of its aryl alkenoic substituent showed potency against NCI-H322 (bronchioloalveolar carcinoma), and A549 (lung adeno carcinoma) cell lines. [InlineMediaObject not available: see fulltext.].

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