75446-92-3 Usage
Description
1(2H)-Isoquinolinone, 4-hydroxy-3-phenyl-2-(phenylmethyl)-, commonly known as papaverine, is a derivative of the alkaloid papaverine. It is a chemical compound with significant pharmacological properties, primarily recognized for its smooth muscle relaxant effects. Papaverine functions by inhibiting the phosphodiesterase enzyme, which results in increased levels of cyclic adenosine monophosphate (cAMP). This increase in cAMP levels leads to the relaxation of smooth muscles in blood vessels and other organs, making it a valuable compound in the treatment of various medical conditions.
Uses
Used in Pharmaceutical Industry:
Papaverine is used as a smooth muscle relaxant for the treatment of vasospastic disorders and erectile dysfunction. Its ability to inhibit the phosphodiesterase enzyme and increase cAMP levels contributes to the relaxation of smooth muscles, which can alleviate symptoms associated with peripheral vascular disease, coronary artery disease, and erectile dysfunction.
However, it is important to note that papaverine may have potential side effects such as hypotension, tachycardia, and flushing. Therefore, it should be used with caution and under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 75446-92-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,4 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 75446-92:
(7*7)+(6*5)+(5*4)+(4*4)+(3*6)+(2*9)+(1*2)=153
153 % 10 = 3
So 75446-92-3 is a valid CAS Registry Number.