75462-61-2 Usage
Uses
Used in Pharmaceutical Industry:
3,5-Bis(trifluoromethyl)toluene is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with enhanced properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3,5-Bis(trifluoromethyl)toluene is utilized as an intermediate to produce compounds that aid in the protection and enhancement of agricultural products.
Used in Dye Industry:
3,5-Bis(trifluoromethyl)toluene is employed as an intermediate in the production of dyes, where its chemical properties contribute to the creation of vibrant and stable colorants.
Used as a Solvent:
3,5-Bis(trifluoromethyl)toluene is used as a solvent in various chemical processes due to its ability to dissolve a wide range of substances and facilitate reactions.
Used as a Reagent in Organic Synthesis:
3,5-BIS(TRIFLUOROMETHYL)TOLUENE is also used as a reagent in organic synthesis, where its unique properties can be leveraged to produce a variety of organic compounds.
Safety Considerations:
It is important to handle 3,5-Bis(trifluoromethyl)toluene with care due to its potential harmful effects if swallowed, inhaled, or in contact with skin. Additionally, it may cause irritation to the eyes and respiratory system, necessitating proper safety measures during its use in industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 75462-61-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,4,6 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 75462-61:
(7*7)+(6*5)+(5*4)+(4*6)+(3*2)+(2*6)+(1*1)=142
142 % 10 = 2
So 75462-61-2 is a valid CAS Registry Number.
75462-61-2Relevant academic research and scientific papers
Selective cleavage of 3,5-bis-(trifluoromethyl)benzylcarbamate by SmI 2-Et3N-H2O
Ankner, Tobias,Said Stalsmeden, Anna,Hilmersson, Goeran
, p. 6867 - 6869 (2013/07/26)
A novel electron poor protection group for amines has been developed. It undergoes rapid cleavage by SmI2-Et3N-H2O and its orthogonality towards the regular benzyl carbamate group (CBz) under reductive or transfer hydrogenolytic conditions is reported.
SmI2/H2O/amine promoted reductive cleavage of benzyl-heteroatom bonds: optimization and mechanism
Ankner, Tobias,Hilmersson, G?ran
experimental part, p. 10856 - 10862 (2010/02/28)
The SmI2/H2O/pyrrolidine mediated cleavage of benzylic alcohols and benzyl groups was studied and found to be a viable alternative to the Birch reduction yielding the corresponding deoxygenated product in excellent yield. The reaction has been investigated by kinetic methods, and a mechanism involving a pre-complexation of the alcohol to SmI2 followed by an amine mediated electron transfer and subsequent bond cleavage and transfer of a second electron and proton to yield the toluene product has been proposed. The reaction is strongly inhibited at higher concentrations of water, indicating that it proceeds via an inner-sphere electron transfer from samarium(II) to the benzyl group, and excess of water prevents coordination of benzyl alcohol to samarium.
