754960-55-9Relevant academic research and scientific papers
Orally active thrombin inhibitors. Part 1: Optimization of the P1-moiety
Mack, Helmut,Baucke, Dorit,Hornberger, Wilfried,Lange, Udo E.W.,Seitz, Werner,Hoeffken, H. Wolfgang
, p. 2641 - 2647 (2008/12/21)
The synthesis and SAR of novel nanomolar thrombin inhibitors with the common backbone HOOC-CH2-d-cyclohexylalanyl-3,4-dehydroprolyl-NH-CH 2-aryl-C(double bond, long NH)NH2 are described together with their ecarin clotting
