754986-03-3Relevant academic research and scientific papers
2 - {-3-`2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY}-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES
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Page/Page column 39, (2008/06/13)
The invention relates to compounds of formula (I), wherein R represents H, CF3; R1 represents H, CF3, a (C1-C6)-alkyl, a phenyl, a phenoxy; R2 represents H, a (C1-C4)-alkyl, O-(C1-C4)-alkyl, CF3; or R1 and R2 represent, together with the phenyl-ring, a condensed naphthyl; R3 represents a (C1-C6)-alkyl; R4 represents a (C1-C6)-alkyl, benzyl; R5 represents H, a (C1-C6)-alkyl. The invention also relates to the physiologically compatible salts thereof, solvates and physiologically functional derivatives. The inventive compounds are suitable for treating and/or preventing disorders of the fatty acid metabolism and disorders of glucose utilization in addition to disorders, in which insulin resistance plays a part.
Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
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Page/Page column 25, (2008/06/13)
Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals The invention relates to arylcycloalkyl-substituted alkanoic acid derivatives and to their physiologically acceptable salts and physiologically functional derivatives. What is described are compounds of the formula I, 1 in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable, for example, for the treatment and/or prevention of disorders of the fatty acid metabolism and glucose utilization disorders and also disorders in which insulin resistance is involved.
