755033-91-1Relevant academic research and scientific papers
A divergent approach to 3-azido-2,3,6-trideoxy-l-hexoses from rhamnal
Zhang, Guisheng,Shi, Lei,Liu, Qingfeng,Liu, Xiaobing,Li, Lu,Wang, Jingmei
, p. 3413 - 3416 (2007)
An alternative strategy has been developed for producing 3-azido-2,3,6-trideoxy-l-hexoses, protected forms of daunosamine, ristosamine, acosamine, and epi-daunosamine. This method involved BF3·OEt2-induced peroxidation of rhamnal to
Syntheses and biological activities of 3′-azido disaccharide analogues of daunorubicin against drug-resistant leukemia
Zhang, Guisheng,Fang, Lanyan,Zhu, Lizhi,Zhong, Yanqiang,Wang, Peng George,Sun, Duxin
, p. 1792 - 1799 (2007/10/03)
Anthracyclines, such as daunorubicin (DNR) and doxorubicin (Dox), are widely used for cancer therapy but are limited by drug resistance and cardiotoxicity. To overcome drug resistance, we synthesized a novel class of disaccharide analogues of DNR against
