755034-31-2

Upstream product

• 755034-30-1 (2-((2-methoxy-4-nitrophenoxy)methoxy)ethyl)trimethylsilane 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 3251-56-7 2-methoxy-4-nitrophenol 

Downstream Products

• 1224172-16-0 ethyl 1-(4-chlorophenyl)-3-(3-methoxy-4-((2-(trimethylsilyl)ethoxy)methoxy)phenylcarbamoyl)-1H-pyrazole-4-carboxylate 
• 1574543-15-9 (3S)-tert-butyl 3-(4-(3-(4-cyclopropylphenoxy)-2-oxopyrrolidin-1-yl)-2-methoxyphenoxy)pyrrolidine-1-carboxylate 
• 1574543-16-0 (3S)-tert-butyl 3-(4-(3-(4-cyclopropylphenoxy)-2-oxopyrrolidin-1-yl)-2-methoxyphenoxy)pyrrolidine-1-carboxylate 
• 1574538-41-2 (R)-3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-((S)-pyrrolidin-3-yloxy)phenyl)pyrrolidin-2-one hydrochloride 
• 1574538-42-3 (S)-3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-((S)-pyrrolidin-3-yloxy)phenyl)pyrrolidin-2-one hydrochloride 
• 1574541-45-9 (±)-3-(4-cyclopropylphenoxy)-1-(4-hydroxy-3-methoxyphenyl)pyrrolidin-2-one 
• 1574542-92-9 (±)-3-(4-cyclopropylphenoxy)-1-(4-(2-hydroxyethoxy)-3-methoxyphenyl)pyrrolidin-2-one 
• 1574543-00-2 3-(4-cyclopropylphenoxy)-1-(4-(2-hydroxyethoxy)-3-methoxyphenyl)pyrrolidin-2-one 
• 1574543-02-4 3-(4-cyclopropylphenoxy)-1-(4-(2-hydroxyethoxy)-3-methoxyphenyl)pyrrolidin-2-one 
• 1574541-46-0 2-(4-(3-(4-cyclopropylphenoxy)-2-oxopyrrolidin-1-yl)-2-methoxyphenoxy)ethyl methanesulfonate 
• 1574541-47-1 (R)-2-(4-(3-(4-cyclopropylphenoxy)-2-oxopyrrolidin-1-yl)-2-methoxyphenoxy)ethyl methanesulfonate 
• 1574538-13-8 (S)-3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)pyrrolidin-2-one 
• 1574538-14-9 3-(4-cyclopropylphenoxy)-1-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)pyrrolidin-2-one 
• 1574541-67-5 (±)-3-(biphenyl-4-yloxy)-1-(3-methoxy-(4-((2-trimethylsilyl)ethoxy)methoxy)phenyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

PYRROLONE OR PYRROLIDINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS

The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments.

AZOLOPYRROLONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS

The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula (I) including all pharmaceutically acceptable salts and stereoisomers thereof: wherein A is a mo

HETEROCYCLIC KINASE INHIBITORS

Compounds having the formula (I) are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.