75507-25-4

Basic information

• Product Name: 2-HYDROXYMETHYL-15-CROWN-5
• Synonyms: 1,4,7,10,13-PENTAOXACYCLOPENTADECANE-2-METHANOL;2-HYDROXYMETHYL-15-CROWN-5;2-(HYDROXYMETHYL)-15-CROWN 5-ETHER;2-(HYDROXYMETHYL)-1,4,7,10,13-PENTAOXACYCLOPENTADECAN;2-(HYDROXYMETHYL)-1,4,7,10,13-PENTAOXACYCLOPENTADECANE;1,4,7,10,13-Pentaoxacyclopentadecane-3-methanol;Hydroxy-15-crown-5;2-Hydroxymethyl-15-crown-5,96%
• CAS NO: 75507-25-4
• Molecular Formula: C₁₁H₂₂O₆
• Molecular Weight: 250.29
• EINECS: 278-222-4
• Product Categories: Crown Ethers;Functional Materials;Macrocycles for Host-Guest Chemistry
• Mol File: 75507-25-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 135 °C1.5 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /Liquid
• Density: 1.175 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.23E-08mmHg at 25°C
• Refractive Index: n20/D 1.479(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Soluble in water(58 g/L) (25°C).
• BRN: 3589706
• CAS DataBase Reference: 2-HYDROXYMETHYL-15-CROWN-5(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXYMETHYL-15-CROWN-5(75507-25-4)
• EPA Substance Registry System: 2-HYDROXYMETHYL-15-CROWN-5(75507-25-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 75507-25-4(Hazardous Substances Data)

Usage

Uses

2-Hydroxymethyl-15-crown-5 is used for chemical research.

InChI:InChI=1/C11H22O6/c12-9-11-10-16-6-5-14-2-1-13-3-4-15-7-8-17-11/h11-12H,1-10H2/t11-/m1/s1

Upstream product

• 75507-17-4 benzyl 2,4,7,10,13-pentaoxacyclopentadecan-2-ylmethyl ether 
• 114951-76-7 1-(benzyloxymethyl) triethylene glycol 
• 112-60-7 Tetraethylene glycol 
• 638-56-2 1,11-dichloro-3,6,9-trioxaundecane 
• 41024-91-3 penta(ethylene glycol) bis(p-toluenesulfonate) 
• 37860-51-8 tetraethylene glycol di(p-toluenesulfonate) 
• 68167-86-2 1-allyloxymethyl-3,6,9,12,15-pentaoxacyclopentadecane 

Downstream Products

• 84130-97-2 (15-crown-5)methyl 4-nitrobenzoate 
• 94978-67-3 2-((2,4-dinitrophenyl)methyl)-15-crown-5 
• 288143-56-6 3-chloromethylbenzoic acid 1,4,7,10,13-pentaoxacyclopentadec-2-ylmethyl ester 
• 88817-35-0 <10-(p-aminophenoxy)-2,5,8-trioxadecyl>-15-crown-5 
• 1250366-65-4 C₃₀H₄₁ClO₁₀ 
• 84131-00-0 2-<(tosyloxy)methyl>-15-crown-5 
• 87453-21-2 2-((4-nitrophenoxy)methyl)-15-crown-5 
• 84130-96-1 (15-crown-5)methyl 4-methoxybenzoate 
• 84130-95-0 (15-crown-5)methyl benzoate 
• 143773-19-7 C₃₇H₄₄O₁₂ 
• 144381-56-6 sodium monoethyl 5-<(1,1-dimethyl)decyl>-2-(oxymethyl-15-crown-5)methylbenzenephosphonate 

Relevant articles and documents

Bonded crown ether type adsorbent as well as preparation method and application thereof

The invention provides a bonded crown ether type adsorbent as well as a preparation method and application thereof. Based on the application of the novel bonded crown ether type adsorbent provided bythe invention in polyether refining, alkali metals in polyether can be effectively reduced, and meanwhile, the odor of polyether is reduced to the maximum extent; and the adsorbent provided by the invention has the advantages of reproducibility and strong adsorption capacity. The preparation method of the bonded crown ether type adsorbent comprises the following steps: (1) adding alkali A into a mixed solution of ethylene glycol and an organic solvent A, heating and refluxing a reaction system after the alkali A is dissolved, dropwise adding a halogenated epoxy compound into the reaction system, and obtaining an intermediate product A after a reflux reaction is finished; (2) mixing the intermediate product A with an organic solvent B, adding alkali B into the mixed solution, heating for reflux reaction, performing purifying and acidifying after the reaction is finished to obtain an intermediate product B; and (3) mixing the intermediate product B with diaryliodonium salt for reaction to generate the bonded crown ether adsorbent.

Alkali-Metal Cation Recognition Induced Isomerization of Spirobenzopyrans and Spironaphthoxazins Possessing a Crown Ring as a Recognition Site: Multifunctional Artificial Receptors

Spirobenzopyrans and spironaphthoxazins possessing a monoaza-crown ring were synthesized.Isomerization of these compounds to the open colored merocyanines was induced by recognition of alkali-metal cations and the selectivity of the coloration was found to be governed by several factors: (1) the size of the crown ring, (2) the position of recognition, (3) electric properties of both the complexed cations and the merocyanine dipoles, and (4) the length of the alkyl chains connecting the spirobenzopyran units and the crown units.The spirobenzopyrans represent rationally designed multifunctional receptors for alkali-metal cations.

Facile Synthesis of Hydroxymethylcrown Ethers

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