75516-79-9Relevant academic research and scientific papers
X=Y-ZH Systems as Potential 1,3-Dipoles. Part 7. Stereochemistry of the Cycloaddition of Imines of α-Amino Acid Esters to Fumarate and Maleate Esters
Grigg, Ronald,Kemp, James,Warnock, William J.
, p. 2275 - 2284 (2007/10/02)
Aryl imines of α-amino acid esters undergo 1,3-dipolar cycloadditions with maleate and fumarate esters in quantitative yield when heated in boiling toluene to give mixtures of mainly two pyrrolidines.The major isomer in each case arises from cycloaddition
X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. THE STEREOCHEMISTRY AND REGIOCHEMISTRY OF CYCLOADDITION REACTIONS OF IMINES OF α-AMINO-ACID ESTERS.
Grigg, Ronald,Kemp, James
, p. 2461 - 2464 (2007/10/02)
The stereochemistry and regiochemistry of cycloadditions of α-amino acid ester imines is dependent both on imine structure and on the reactivity of the dipolarophile.Phenylglycine imines undergo competing dipole stereomutation and cycloaddition with some dipolarophiles.
