7554-21-4Relevant academic research and scientific papers
Oxidative amidation of benzyl alcohols with amino acid esters mediated by N-hydroxysuccinimide/phenyliodine diacetate
Mahesh, Mandipogula,Panduranga, Veladi,Prabhu, Girish,Kumar L, Roopesh,Ramana, P. Venkata,Sureshbabu, Vommina V.
, p. 716 - 721 (2017)
A simple protocol involving metal-free oxidative amidation of benzyl alcohols with amino acid esters has been presented. The amidation proceeds in a radical pathway unlike in conventional metal-mediated extrusion of dihydrogen. The method is advantageous in terms of metal-free conditions, nonexpensive commercial starting substrates. Also various substituents in the starting materials are tolerated and sterically hindered amino acid side chains could provide good yields of amide products.
Br?nsted acid catalyzed dynamic kinetic resolution of azlactones for the synthesis of aryl glycine derivatives
Wang, Chao,Luo, Hong-Wen,Gong, Liu-Zhu
supporting information; experimental part, p. 992 - 994 (2011/06/17)
The dynamic kinetic resolution of C4-aryl azlactones with alcohols was investigated by employing Br?nsted acid catalysis. The reaction provided an efficient complementary approach to access chiral aryl glycine derivatives with excellent yields (up to 99%)
Self-association-free dimeric cinchona alkaloid organocatalysts: Unprecedented catalytic activity, enantioselectivity and catalyst recyclability in dynamic kinetic resolution of racemic azlactones
Woong Lee, Ji,Hi Ryu, Tae,Suk Oh, Joong,Yong Bae, Han,Bin Jang, Hyeong,Eui Song, Choong
supporting information; scheme or table, p. 7224 - 7226 (2010/03/25)
Self-association-free, bifunctional, squaramide-based dimeric cinchona alkaloid organocatalysts show unprecedented catalytic activity, enantioselectivity and catalyst recyclability in the dynamic kinetic resolution (DKR) reaction of a broad range of racemic azlactones. The Royal Society of Chemistry 2009.
