7555-94-4

Basic information

• Product Name: 4-Methoxy-2,3-dihydro-1H-indole
• Synonyms: 4-METHOXY-2,3-DIHYDRO-1H-INDOLE;1H-Indole, 2,3-dihydro-4-methoxy-;4-methoxyindoline
• CAS NO: 7555-94-4
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Product Categories: API intermediates
• Mol File: 7555-94-4.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 278.058°C at 760 mmHg
• Flash Point: 104.252°C
• Appearance: /
• Density: 1.077g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.96±0.20(Predicted)
• CAS DataBase Reference: 4-Methoxy-2,3-dihydro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-2,3-dihydro-1H-indole(7555-94-4)
• EPA Substance Registry System: 4-Methoxy-2,3-dihydro-1H-indole(7555-94-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 7555-94-4(Hazardous Substances Data)

Usage

General Description

4-Methoxy-2,3-dihydro-1H-indoIe is a chemical compound often used in scientific research and pharmaceutical development. As indicated by its name, its structure features an indole ring system, which is a common skeleton in a range of natural products and pharmaceuticals. The presence of a methoxy group and a saturated dihydroindole ring differentiates it from other indole derivatives. This specific structure could impart unique chemical and biological properties, making it an essential tool in the creation and testing of new synthetic compounds. Its handling and use require special precautions due to its potential reactivity and the need for precise control over its concentration.

InChI:InChI=1/C9H11NO/c1-11-9-4-2-3-8-7(9)5-6-10-8/h2-4,10H,5-6H2,1H3

Upstream product

• 2380-94-1 1H-indol-4-ol 
• 4837-90-5 4-methoxy-1H-indole 
• 2045-79-6 o-methoxy-2-phenylethylamine 

Downstream Products

• 295325-62-1 1-[(S)-(4-amino-4-carboxybutanoyl)]-4-methoxy-7-nitroindoline 
• 4837-90-5 4-methoxy-1H-indole 
• 1316316-45-6 1-(2-aminoacetyl)-4-methoxy-7-nitroindoline hydrochloride 
• 278794-25-5 2-Hydroxy-3-(4-methoxyindolin-1-yl)-3-phenylpropanol 
• 314760-17-3 4-methoxy-7-nitrosoindole 
• 881829-87-4 {1-[2-(1,1-diphenylethylsulfanyl)ethyl]-2,3-dihydro-1H-indol-4-yloxy}acetic acid methyl ester 

Relevant articles and documents

Development of 4-methoxy-7-nitroindolinyl (MNI)-caged auxins which are extremely stable in planta

Phytohormone auxin is a master regulator in plant growth and development. Regulation of cellular auxin level plays a central role in plant development. Auxin polar transport system modulates an auxin gradient that determines plant developmental process in

Synthesis of a caged glutamate for efficient one- and two-photon photorelease on living cells

We have synthesized a biologically inert, photosensitive derivative of the major excitatory amino acid, L-glutamate (which we call MDNI-glu) that makes more efficient use of incident light than all other caged glutamates. Laser flash photolysis of MDNI-glu in acutely isolated hippocampal brain slices evoked a rapid increase in intracellular Ca2+ concentration in astrocytes. The Royal Society of Chemistry 2005.

Lactam derivative as well as preparation method and medical application thereof

The invention relates to lactam derivatives, and a preparation method and medical application thereof. Specifically, the invention relates to lactam derivatives as shown in a general formula (I), a preparation method of the lactam derivatives, pharmaceuti

HYDROGELS AND USE THEREOF IN ANASTOMOSIS PROCEDURES

This disclosure provides novel hydrogels that can undergo multiple gel-sol transitions and methods of making and using such hydrogels, particularly in anastomosis procedures. The peptide hydrogels comprising a fibrillar network of peptides that are in an amphiphilic β-hairpin conformation. The peptides comprise photo-caged glutamate residues with a neutral photocage that can be photolytically selectively uncaged to disrupt the fibrillar network and trigger an irreversible gel- sol phase transition of the hydrogel. Isolated peptides for making the disclosed hydrogels are provided, as are methods of using the peptide hydrogels in anastomosis procedures.