75581-65-6Relevant academic research and scientific papers
Synthesis of 2-amino-2-cyanoadamantane and its derivatives
Popov, Yu. V.,Mokhov, V. M.,Tankabekyan, N. A.,Safronova, O. Yu.
, p. 1387 - 1394,8 (2012/12/12)
Synthetic routes to new amino nitriles with the functional groups at the 2-position of the adamantane core, based on reactions of adamantanonimines with acetone cyanohydrin or of adamantanone cyanohydrin with aliphatic amines, are considered. The products can be used for preparing new biologically active substances, unsymmetrical adamantyl-containing diamines or amino acids.
Synthesis of 2-amino-2-cyanoadamantane and its derivatives
Popov, Yu.V.,Mokhov,Tankabekyan,Safronova, O. Yu.
, p. 1387 - 1394 (2013/01/15)
Synthetic routes to new amino nitriles with the functional groups at the 2-position of the adamantane core, based on reactions of adamantanonimines with acetone cyanohydrin or of adamantanone cyanohydrin with aliphatic amines, are considered. The products can be used for preparing new biologically active substances, unsymmetrical adamantyl-containing diamines or amino acids. Pleiades Publishing, Ltd., 2012.
SYNTHESIS AND TRANSFORMATIONS OF OXAZIRIDINES. ADAMANTANE-2-SPIRO-3'-OXAZIRIDINE AND ITS N-ALKYL DERIVATIVES
Novoselov, E. F.,Isaev, S. D.,Yurchenko, A. G.
, p. 97 - 103 (2007/10/02)
Unsubstituted and N-substituted adamantane-2-spiro-3'-oxaziridine were synthesized by the oxidation of Schiff bases, obtained from adamantanone and alkyl(aryl)amines, with peroxyacetic acid.The thermal rearrangement of the N-substituted derivatives leads to N-substituted 5-azahomoadamantan-4-ones, while fragmentation under the influence of Fe(II) ions leads to derivatives of bicyclononane in the form of N-substituted amides.Adamantane-2-spiro-3'-oxaziridine gives different transformation products, i.e., adamantanone in the first case and 5-azahomoadamantan-4-one in the second.
