75584-64-4

Upstream product

• 64-17-5 ethanol 
• 555-21-5 4-Nitrophenylacetonitrile 

Downstream Products

• 141246-11-9 3-[5-Methyl-2-(4-nitro-benzyl)-benzoimidazol-1-yl]-butyric acid 
• 141246-05-1 3-[5-Chloro-2-(4-nitro-benzyl)-benzoimidazol-1-yl]-butyric acid 
• 76751-75-2 N-[2'-(2-Dimethylamino-ethylamino)-biphenyl-2-yl]-2-(4-nitro-phenyl)-acetamide 
• 76751-76-3 N-[2'-(3-Dimethylamino-propylamino)-biphenyl-2-yl]-2-(4-nitro-phenyl)-acetamide 
• 76751-77-4 2-amino>-2'-amino>biphenyl 
• 76751-78-5 N-[2'-(3-Diethylamino-propylamino)-biphenyl-2-yl]-2-(4-nitro-phenyl)-acetamide 
• 112030-58-7 2-(4-nitrobenzyl)-4,5-dihydro-1H-imidazole 
• 112030-61-2 2-(4-Nitro-benzyl)-1,4,5,6-tetrahydro-pyrimidine 
• 76751-82-1 2-(4-Amino-phenyl)-N-[2'-(2-dimethylamino-ethylamino)-biphenyl-2-yl]-acetamide 
• 76751-83-2 2-(4-Amino-phenyl)-N-[2'-(2-diethylamino-ethylamino)-biphenyl-2-yl]-acetamide 
• 141245-88-7 3-<2-(4-Amino)benzylbenzimidazol-1-yl>butanoic acid 
• 141245-89-8 3-<2-(4-Acetylamino)benzylbenzimidazol-1-yl>butanoic acid 
• 39695-96-0 2-(4-nitrophenyl)ethanimidamide hydrochloride 
• 783278-00-2 2-(4-nitrophenyl)methylimidazole 

Relevant academic research and scientific papers

Guest recognition with micelle-bound cavitands

We report that a benzimidazole cavitand is incorporated in aqueous phosphocholine (PC) micelles, folds into the vase conformation, and functions as small-molecule host. As a micelle-bound host it has the ability to sequester selective hydrophobic guest "a

Colchicine derivatives, and preparation method and medical application thereof

The invention specifically relates to colchicine derivatives (I) as described in the specification and a preparation method thereof, and pharmaceutical compositions containing the colchicine derivatives, belonging to the field of medicinal chemistry. The results of pharmacodynamic experiments prove that the colchicine derivatives of the invention have treatment effect on lumbar disc herniation andliver fibrosis.

Copper(II)-Mediated Aerobic Oxidation of Benzylimidates: Synthesis of Primary α-Ketoamides

A simple and straightforward method for the synthesis of primary α-ketoamides has been discovered. The reaction represents the first example of benzylimidates directly converting to primary α-ketoamides by using sustainable molecular oxygen as an oxidant. This reaction proceeds in the presence of copper(II) salt via cleavage of benzylic C-H and C-O bonds of the benzylimidates with liberation of alcohols as the only byproduct. A wide substrate scope, operationally mild conditions, the use of single substrates, and a reaction scaled up to grams make this strategy very attractive and practical. Furthermore, mechanistic studies illustrate that the imidate group adjacent to the benzylic position plays crucial role in facilitating this chemical process.

Two new types of π-conjugation between a fullerene sphere and an addend

Diazirine addition reactions to C60, followed by an HCl elimination step, yielded [6,6] and [5,6] sp2 carbon bridged fullerenes. The [5,6] adducts (alkylidenehomofullerenes) are the first examples of fullerene structures where the ad

2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS

The invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. These compounds are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

IMIDAZO[1,2-C]PYRIMIDINYLACETIC ACID DERIVATIVES

The present invention relates to an imidazo[1,2-c]pyrimidinylacetic acid derivative and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The imidazo[1,2-c]pyrimidinylacetic acid derivative of the present invention has

Synthesis and cytotoxicity of substituted 2-benzylnaphth[2,3-d]imidazoles

Designed as a new series of so called "bivalent ligand" containing the proposed 2-benzylnaphthimidazole-type structure, a number of 2-benzylnaphth[2,3-d]imidazoles, bearing various substituents, have been prepared by a synthetic approach involving an hete

Synthesis and choleretic activity of 3-[2-(3-R', 4-R'', 5-R'''-benzyl)-5- R-benzimidazol-1-yl]-butanoic acids

On the ground of the evidentiated choleretic activity of 3-[2- benzylbenzimidazol-1-yl]butanoic acid, 28 new acids were prepared in order to evaluate the influence of suitable substitutions in either C5 of heteroring or C3', C4', C5' of benzyl group in po

Synthesis and Antiinflammatory Activity of 2,2'-Diaminobiphenyl Derivatives

A series of 2,2'-diaminobiphenyl derivatives was prepared and tested for antiinflammatory activity.Several compounds showed antiinflammatory activity, particularly 2-amino>-2'-amino>biphenyl (4), which als