755889-33-9Relevant academic research and scientific papers
Benzodiazepine inhibitors of the MMPs and TACE. Part 2
Levin, Jeremy I.,Nelson, Frances C.,Delos Santos, Efren,Du, Mila T.,MacEwan, Gloria,Chen, James M.,Ayral-Kaloustian, Semiramis,Xu, Jun,Jin, Guixian,Cummons, Terri,Barone, Dauphine
, p. 4147 - 4151 (2007/10/03)
A series of benzodiazepine MMP/TACE inhibitors bearing polar moieties has been synthesized in an effort to optimize inhibitory activity against LPS-stimulated TNF production in human monocytes and oral activity in a murine LPS model.
