75593-19-0Relevant academic research and scientific papers
Regio- and Stero-selective Desulphurizative γ-Substitution of α-Substituted β-Methylallyl Sulphoxides and Sulphones with Lithium Dialkylcuprates providing Trisubstituted Olefins
Masaki, Yukio,Sakuma, Kazuhiko,Kaji, Kenji
, p. 1170 - 1176 (2007/10/02)
α-Substituted β-methylallyl sulphoxides (2) and sulphones (3) undergo regio- and stereo-selective desulphurizative γ-substitution by the action of lithium dialkylcuprates in ether.The reaction provides a new method for the synthesis of trisubstituted E-ol
FACILE FUNCTIONALIZATION OF THE ISOPROPYLIDENE TERMINUS OF ACYCLIC MONOTERPENES BY WAY OF BENZENESULFENYL CHLORIDE ADDITION
Masaki, Yukio,Hashimoto, Kinji,Kaji, Kenji
, p. 3481 - 3490 (2007/10/02)
Highly site- and regioselective terminal functionalizations of acyclic monoterpenes 1 via benzenesulfenyl chloride addition followed by hydrolysis assisted by silica gel, dehydrochlorination under neutral or weakly basic condition, or dehydrochlorination by strongly basic treatment respectively providing β-hydroxy sulfides 3, terminal methallylic sulfides 4, or vinylsulfides 5 are developed.Conversion of 4 to terminal trans-allylic alcohols 10 via sulfoxides 9 by the Evans procedure is also described.
