75613-96-6Relevant academic research and scientific papers
1,2-Dicarbofunctionalization of Trifluoromethyl Alkenes with Pyridinium Salts via a Cycloaddition/Visible-Light-Enabled Fragmentation Cascade
Chen, Guo-Shu,Chen, Shu-Jie,Deng, Tao,He, Zhi-Qing,Li, Jia-Hui,Liu, Li-Shan,Liu, Yun-Lin,Ren, Hai
supporting information, p. 702 - 707 (2022/01/28)
Although trifluoromethyl alkenes have great synthetic potential, their 1,2-difunctionalization has been a challenge. In this Letter, we disclose the first 1,2-dicarbofunctionalization of trifluoromethyl alkenes with pyridinium salts via a cascade process
Synthesis of benzoindolizine derivatives by reaction of trimethyl phosphite, dialkyl acetylenedicarboxylates and isoquinolinium or quinolinium bromides
Anary-Abbasinejad, Mohammad,Charkhati, Khadije,Hassanabadi, Alireza
experimental part, p. 95 - 97 (2009/11/30)
The reactive 1:1 adduct produced by the addition of trimethyl phosphite to dialkyl acetylenedicarboxylates protonated by isoquinolinium or quinolinium bromides to afford isoquinolinium or quinolinium ylides and vinyl phosphonium bromides. 1,3-Dipolar cycl
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions
Kemnitzer, William,Kuemmerle, Jared,Jiang, Songchun,Zhang, Han-Zhong,Sirisoma, Nilantha,Kasibhatla, Shailaja,Crogan-Grundy, Candace,Tseng, Ben,Drewe, John,Cai, Sui Xiong
scheme or table, p. 6259 - 6264 (2009/07/18)
1-Benzoyl-3-cyanopyrrolo[1,2-a]quinoline (2a) was identified as a novel apoptosis inducer through our caspase- and cell-based high-throughput screening assay. Compound 2a had good activity against several breast cancer cell lines but was much less active
Syntheses and cytotoxic, antimicrobial, antifungal and cardiovascular activity of new quinoline derivatives
Khan,Saify,Khan,Ahmed,Saeed,Schick,Kohlbau,Voelter
, p. 915 - 924 (2007/10/03)
New derivatives of quinoline (CAS 91-22-5, Z-1) were synthesized and their potential therapeutical significance and structure-activity relationship were tested. The brine shrimp bioassay was carried out to study their in vitro cytotoxicity, and besides, a
