75613-96-6Relevant articles and documents
1,2-Dicarbofunctionalization of Trifluoromethyl Alkenes with Pyridinium Salts via a Cycloaddition/Visible-Light-Enabled Fragmentation Cascade
Chen, Guo-Shu,Chen, Shu-Jie,Deng, Tao,He, Zhi-Qing,Li, Jia-Hui,Liu, Li-Shan,Liu, Yun-Lin,Ren, Hai
supporting information, p. 702 - 707 (2022/01/28)
Although trifluoromethyl alkenes have great synthetic potential, their 1,2-difunctionalization has been a challenge. In this Letter, we disclose the first 1,2-dicarbofunctionalization of trifluoromethyl alkenes with pyridinium salts via a cascade process
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions
Kemnitzer, William,Kuemmerle, Jared,Jiang, Songchun,Zhang, Han-Zhong,Sirisoma, Nilantha,Kasibhatla, Shailaja,Crogan-Grundy, Candace,Tseng, Ben,Drewe, John,Cai, Sui Xiong
scheme or table, p. 6259 - 6264 (2009/07/18)
1-Benzoyl-3-cyanopyrrolo[1,2-a]quinoline (2a) was identified as a novel apoptosis inducer through our caspase- and cell-based high-throughput screening assay. Compound 2a had good activity against several breast cancer cell lines but was much less active
