75617-36-6

Upstream product

• 73035-26-4 ethyl 6-amino-5-cyano-2,4-diphenyl-4H-pyran-3-carboxylate 
• 17451-18-2 (Z)-2-benzoyl-3-phenylacrylic acid ethyl ester 
• 100784-57-4 3-cyano-5-ethoxycarbonyl-6-hydroxy-4,6-diphenylpiperidin-2-one 
• 105199-40-4 Sodium; (4R,5S,6R)-3-cyano-5-ethoxycarbonyl-6-hydroxy-4,6-diphenyl-1,4,5,6-tetrahydro-pyridine-2-thiolate 
• 105199-50-6 5-Cyano-2,4-diphenyl-6-thioxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester 
• 105199-55-1 2,2'-Bis(4,6-diphenyl-5-ethoxycarbonyl-3-cyanopyridyl)disulfide 
• 75617-38-8 3-cyano-5-ethoxycarbonyl-4,6-diphenyl-3,4-dihydropyridin-2(1H)-one 
• 105199-60-8 4,6-Diphenyl-5-ethoxycarbonyl-3-cyanopyridine-2(1H)thione 

Relevant academic research and scientific papers

Synthesis of Heterocyclic Compounds, L. - Preparation of Ethyl 2,4-Diaryl-5-cyano-1,6-dihydro-6-thioxo-3-pyridinecarboxylates from Ethyl α-Benzoylcinnamates

Die Umsetzung von α-Benzoylzimtsaeure-ethylestern 2 mit Cyanthioacetamid (1) in Methanol/Natriummethanolat fuehrt zu den Natriumsalzen der 2,4-Diaryl-5-cyan-1,2,3,4-tetrahydro-2-hydroxy-6-mercapto-3-pyridincarbonsaeure-ethylester 3.Diese koennen zu Methylthio-Derivaten 4 methyliert oder zu Dihydropyridonen 5 dehydratisiert werden.Die Verbindungen 4 werden mittels Nitrosylschwefelsaeure zu den entsprechenden aromatischen 2-(Methylthio)pyridinen oxidiert.Andererseits fuehrt eine aehnliche Behandlung der Derivate 5 zwar zu Aromatisierung, aber isoliert werden die Disulfide 6.Reduktion dieser Disulfide ergibt 2-Thiopyridone 7, woraus die zu gehoerigen 2-Pyridone 9 hergestellt werden koennen.Diese Produkte entstehen auch bei der basischen Hydrolyse von (Methylthio)pyridinen 8.

Reactivity of Heterocyclic Compounds. VI. 2,6-Diaminopyrimidine-5-carbonitriles and 3,5-Dicyanopyridones from 2-Amino-4H-pyran-3,5-dicarbonitriles

The reaction of different 2-amino-4H-pyrans (1, 10) with guanidine affords 2,6-diaminopyrimidine derivatives (3).Treatment of the pyrans mentioned or their acetylated derivatives with trityl tetrafluoroborate does not yield pyrylium salts, and pyrid-2-one

Synhesis of Heterocyclic Compounds. Part 46. The reactions of Malonamide and 2-Cyanoacetamide with Substituted Propenones

The synthesis of substituted 2-pyridone derivatives from malonamide (1) and 2-cyanoacetamide (2) is reported.Conjugate addition of these compounds to substituted propenones (3) and (4) leads to 6-hydroxy-2-piperidones, which can be dehydrated and aromatiz

Ring Transformations of 4H-Pyrans. Pyridines from 2-Amino-4H-Pyrans

Ring transformations of 4H-pyrans into pyridines are reported.Treatment of 2-amino-4,6-diaryl-3,5-dicyano-4H-pyrans (I) with nitrosylsulfuric acid brings about their transformation into 3,5-dicyano-4,6-diaryl-2-pyridones (VI) which can also be obtained fr