75628-90-9

Upstream product

• 90-44-8 anthracen-9(10H)-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant academic research and scientific papers

Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer

The human androgen receptor plays a major role in the development and progression of prostate cancer and represents a well-established drug target. All clinically approved androgen receptor antagonists possess similar chemical structures and exhibit the s

Synthesis and antitumor activity of 10-substituted benzylidene anthrone

Fifteen compounds of 10-substituted benzylidene anthrone were prepared with moderate yield by reaction of anthrone and substituted benzaldehydes under the presence of pyridine and piperidine as catalyst. Their antitumor activities in vitro were evaluated.

Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization

A novel series of 10-benzylidene-9(10H)-anthracenones and 10-(phenylmethyl)-9(10H)-anthracenones were synthesized and evaluated for antiproliferative activity in an assay based on K562 leukemia cells. The 3-hydroxy-4-methoxybenzylidene analogue 9h was fou

A facile synthesis of 10-arylmethylene anthracenones under microwave irradiation

10-Arylmethylene anthracenones were synthesised by the condensation of aromatic aldehydes with anthracenone using sodium hydroxide as catalyst under microwave irradiation in good yields.